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目的:探讨纳洛酮治疗饮酒致头孢类抗生素双硫仑样反应的疗效和安全性。方法:饮酒致头孢类抗生素双硫仑样反应患者126例,均给予吸氧,静脉滴注质量分数10%葡萄糖注射液500 mL+维生素C 3 g+氯化钾针10 mL等对症综合治疗,并静脉给予纳洛酮。结果:126例患者均治愈,均未发生不良反应及后遗症。结论:及时诊断并给予纳洛酮静脉滴注等综合治疗措施,可有效治疗饮酒致双硫仑样反应。
Objective: To investigate the efficacy and safety of naloxone in the treatment of disulfiram-like reactions of cephalosporins to alcohol. Methods: 126 cases of cephalosporin antibiotic-induced disulfiram-like reaction were given alcohol and intravenous infusion of 10% glucose injection 500 mL + vitamin C 3 g + potassium chloride needle 10 mL and other symptomatic treatment, and intravenous Give naloxone. Results: All 126 patients were cured. No adverse reactions and sequelae occurred. Conclusion: Timely diagnosis and administration of naloxone, such as intravenous drip, can effectively treat disulfiram-like reactions in alcohol consumption.