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目的 :探讨喉部鳞状细胞癌的发病机制。方法 :采用Northern印迹法检测喉部鳞状细胞癌中表皮生长因子受体mRNA的表达。结果 :在喉部鳞状细胞癌中可见 5 80 0mRNA异常表达。结论 :喉部鳞状细胞癌的生物学行为与其 5 80 0mRNA介导异常表达密切相关。
Objective: To investigate the pathogenesis of laryngeal squamous cell carcinoma. Methods: Northern blotting was used to detect the expression of epidermal growth factor receptor mRNA in laryngeal squamous cell carcinoma. Results: Abnormal expression of 580o mRNA was found in laryngeal squamous cell carcinoma. Conclusion: The biological behavior of laryngeal squamous cell carcinoma is closely related to the abnormal expression of 5 80 0 mRNA.