改变药物的化学结构是改善药物的药代动力学和药学特性以及减少副作用的途径之一。前体药物则是化学结构的暂时性改变。由两种成份结合成的,每一种均具有药理活性且每一种又各自作为另一种的前体药物而发挥作用的前体药物称之为“相互性前体药物“(mutual prodrugs)。扑炎痛是扑热息痛的乙酰水杨酸酯,即为相互性前体药物。近年来,对于研制扑热息痛的新前体药物又再 Changing the chemical structure of a drug is one of the ways to improve the pharmacokinetics and pharmacological properties of the drug and to reduce its side effects. Prodrugs are temporary changes in chemical structure. Prodrugs that combine two components and each have pharmacological activity and each act as a prodrug another are referred to as “mutual prodrugs” . Paesitis pain is paracetamol acetylsalicylate, which is a mutual prodrug. In recent years, new prodrugs have been developed for the development of paracetamol