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回顾性分析2004年1月-2014年12月宁波市妇女儿童医院儿科临床诊断的47例儿童并殖吸虫病例临床资料。结果显示,47例患儿中,男童32例,占68.1%,女童15例,占31.9%。城区患儿24例,发病率为51.1%,农村患儿23例,发病率为48.9%,两者差异无统计学意义(P>0.05)。2010年后学龄前儿童病例有增多趋势。43例有食生或半生溪蟹史,4例有饮生溪水史。2例为并殖吸虫脑病,1例伴有皮下结节。39例患儿外周血嗜酸粒细胞绝对数及百分比均升高,29例患儿血清总Ig E数值升高。47例患儿痰液和粪便中均未检出并殖吸虫卵;经斑点免疫金渗滤法(DIGFA)和ELISA检测,并殖吸虫抗体阳性率均为100%。47例患儿均在确诊后经吡喹酮治疗,治疗过程中均未出现明显不良反应。
The clinical data of 47 paragonimiasis children diagnosed clinically from January 2004 to December 2014 in Ningbo Pediatric Children’s Hospital were retrospectively analyzed. The results showed that 47 cases of children, 32 cases of boys, accounting for 68.1%, 15 girls, accounting for 31.9%. 24 cases of urban children, the incidence was 51.1%, 23 cases of rural children, the incidence was 48.9%, the difference was not statistically significant (P> 0.05). Post-2010 cases of preschool children have an increasing trend. 43 cases of raw or half-life of crabs history, 4 cases of drinking raw water history. 2 cases of paragonimiasis encephalopathy, 1 case accompanied by subcutaneous nodules. The absolute number and percentage of peripheral blood eosinophils in 39 children were increased, and the serum total IgE in 29 children increased. Paragonimus eggs were not found in sputum and faeces of 47 children. The positive rate of Paragonimus antibody was 100% by DIGFA and ELISA. 47 cases were diagnosed with praziquantel after treatment, no significant adverse reactions during the treatment.