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目的探讨降钙素原(PCT)、C-反应蛋白(CRP)在支气管哮喘住院患儿诊治过程中的临床价值。方法选取2011年10月至2012年3月在柘城县人民医院儿科确诊为支气管哮喘住院患儿共50例,健康对照组30例,所有研究对象均抽血检测PCT及CRP,以PCT>0.01 ng/ml、CRP>8 mg/L为阳性结果。结果 50例支气管哮喘患儿PCT、CRP在住院患儿组较健康对照组明显升高,差异有统计学意义(P<0.05),在支气管哮喘患儿组内PCT敏感性、特异性均高于CRP,统计学差异有意义(P<0.05)。结论 PCT、CRP检测对支气管哮喘住院患儿有一定的诊疗价值,在敏感性、特异性等方面均优于CRP。
Objective To investigate the clinical value of procalcitonin (PCT) and C-reactive protein (CRP) in the diagnosis and treatment of hospitalized children with bronchial asthma. Methods From October 2011 to March 2012, 50 children hospitalized with bronchial asthma in pediatric patients in Tancheng County People’s Hospital and 30 healthy controls were enrolled in this study. All subjects were tested for PCT and CRP by blood sampling, and PCT> 0.01 ng / ml, CRP> 8 mg / L positive results. Results The PCT and CRP levels in 50 children with bronchial asthma were significantly higher in hospitalized children than those in healthy controls (P <0.05). The sensitivity and specificity of PCT in children with bronchial asthma were significantly higher than those in healthy children CRP, statistical significance (P <0.05). Conclusion The detection of PCT and CRP has certain value in diagnosis and treatment of hospitalized children with bronchial asthma, and is superior to CRP in sensitivity and specificity.