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目的总结子宫内膜症生育指数(EFI)与术后不同处理方案临床妊娠率的相关性,探讨EFI评分对子宫内膜异位症(EMS)患者术后最佳治疗方案的指导意义。方法总结我院2010年1月到2015年6月106例EMS不孕患者接受腹腔镜手术术后半年的妊娠状况。患者分为3组:期待组(expectant treatment,ET)、自然周期+人工授精(nature cycle plus IUI,NC+IUI)及促排卵+人工授精(controlled ovarian stimulation plus IUI,COS+IUI),对EFI分值与术后半年的累计妊娠率及治疗方案进行回顾性分析,比较术后半年的妊娠情况。结果在各EFI分值组中,EFI分值6分以上患者半年总计妊娠率显著高于6分以下组(P<0.05),NC+IUI及COH+IUI组的半年累计妊娠率均高于期待自然妊娠组。结论 EFI分值高于6分的EMs不孕患者应积极考虑人工授精助孕技术以提高临床妊娠率。
Objective To summarize the correlation between the fertility index (EFI) of endometriosis and the clinical pregnancy rate of different treatment options after operation, and to explore the guiding significance of EFI score on the optimal postoperative treatment for endometriosis patients. Methods From January 2010 to June 2015, 106 pregnant women with EMS infertility who underwent laparoscopic surgery for six months after pregnancy were reviewed. The patients were divided into 3 groups: expectant treatment (ET), nature cycle plus IUI (NC + IUI) and controlled ovarian stimulation plus IUI (COS + IUI) Points and six months after the cumulative pregnancy rate and treatment regimens were retrospectively analyzed, compared with six months after pregnancy. Results In each EFI score group, the half-year total pregnancy rate of patients with EFI score of 6 or more was significantly higher than that of 6-score group (P <0.05). The cumulative pregnancy rates in NC + IUI and COH + IUI groups were higher than expected Natural pregnancy group. CONCLUSIONS: Infertility patients with EMs with an EFI score higher than 6 should actively consider artificial insemination and assisted pregnancy to improve clinical pregnancy rates.