统计近15年来100000例次百白破疫苗注射儿童中发生注射区硬结液化4例。另1例出现严重全身反应、过敏危象，经收院儿科和变态反应科积极抢救，终获治愈。一、临床资料患儿，男，6岁，1990年9月13日上午接受注射百白破疫苗0．5ml，当时无不良反应。回家后进正常饮食，未服任何致 Statistics in the past 15 years, 100000 cases of Baitai broken vaccine injection injection occurred in children with induration in 4 cases. Another case of severe systemic reactions, allergic crisis, the hospital admitted to the active rescue of pediatrics and allergies, and ultimately cured. First, the clinical data of children, male, 6 years old, September 13, 1990 morning injection of diphtheriae vaccine 0.5ml, then no adverse reactions. After returning to normal diet, did not take any cause