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192 1年Ｍｏｎｓｉｅｕｒ经过 13年 2 3 1次传代培养获得了世界上第 1株减毒结核杆菌疫苗———卡介苗 (ＢＣＧ) ,从而改变了整个人类防治结核的历史。半个多世纪后 ,由其衍生出的ＢＣＧ ＤＮＡ、ＣｐＧ寡核苷酸 (ＣｐＧ ＯＤＮ)等不但在防治肿瘤、控制感染、免疫佐剂等方面显
192 1 year Monsieur has changed the history of the entire human control of TB by obtaining the world’s first attenuated Mycobacterium tuberculosis bacillus Calmette-Guérin (BCG) after 13 years of subculture. More than half a century later, the BCG DNA and CpG ODN derived from it have not only played an important role in the prevention and treatment of tumors, infection control and immune adjuvant