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目的:探讨老年患者高同型半胱氨酸(Hcy)高血压(H型高血压)与不稳定型心绞痛(UA)的相关性。方法选择2011年10月~2013年4月我院心内科收治的原发性高血压合并心绞痛的老年患者210例,根据Hcy水平将其分为H型高血压组(n=103例)和单纯高血压组(n=107例),所有患者均进行冠状动脉造影检查,Hcy水平通过酶法测定,比较两组患者血清Hcy水平的差异。结果 H型高血压组不稳定型心绞痛的发生率为46.6%,高敏C反应蛋白(hsCRP)水平为(4.4±1.9)μg/L,冠状动脉病变积分为(45.3±20.1),显著高于单纯高血压组患者UA发生率25.2%,hsCRP水平(2.1±1.8)和冠状动脉病变积分(31.5±17.6),且差异有统计学意义。H型高血压组中,UA和稳定型心绞痛(SA)血清Hcy水平差异有统计学意义;单纯高血压组中,UA与SA比较,血清Hcy和总胆固醇水平差异有统计学意义,老年患者H型高血压是老年UA的独立危险因素。结论老年患者H型高血压与UA密切相关,在老年患者UA的发病和治疗中,既要控制患者血压,又要控制血清Hcy水平。“,”significantly differences between unstable angina cases and stable angina cases in Hcy and total cholesterol levels.H hypertension was an independent risk factor for unstable angina in the elderly.Conclusion H hypertension was closely related to unstable angina in elderly patients.It was necessary to control blood pressure as well as serum Hcy levels in the treatment of unstable angina.