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近年来在苏联不少地区钩端螺旋体病发病率呈上升趋势。为探讨钩端螺旋体病出血综合征的病理机制,并为临床诊治提供依据,作者对近5年来在克拉斯诺达尔传染病医院住院期间病死的30例钩端螺旋体病死者(年龄23～76岁的男性)作了临床流行病学资料分析及尸体解剖检查。结果如下: 15例死亡原因为感染中毒性休克。感染中毒性休克出现的时间,7例在病程的3～4天,5例在病程5～7天,3例在病程的7～9天。死亡时间平均在病程的8±2天。实验室检查发现死者生前出血、凝血时间延长,血中纤维蛋白含量降低,血小板减少,
In recent years, the incidence of leptospirosis in many parts of the Soviet Union is on the rise. To investigate the pathological mechanism of leptospirosis bleeding syndrome and provide a basis for clinical diagnosis and treatment, the author of the past 5 years in the Krasnodar Infectious Diseases hospital died of 30 cases of leptospirosis dead (age 23 to 76 years Of men) made clinical epidemiological data analysis and autopsy examination. The results are as follows: 15 patients died of toxic shock infection. Infected with toxic shock time, 7 cases in the course of 3 to 4 days, 5 cases in the course of 5 to 7 days, 3 cases in the course of 7 to 9 days. The average duration of death is 8 ± 2 days. Laboratory tests found that the deceased bleeding during his lifetime, clotting time, reduced blood fibrinogen, thrombocytopenia,