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目的 对缺氧缺血性脑病 ( HIE)患儿进行随访观察 ,以评价脑电图 ( EEG)在判断 HIE预后中的价值。 方法 对 62例 HIE中存活的 57例患儿进行体格检查及智力测试 ,对异常者行CT、EEG检查 ,评价其临床后遗症与新生儿期 EEG的关系。 结果 62例 HIE患儿新生儿期 EEG显示电静息 3例 ,2例死亡 ,1例偏瘫 ;爆发抑制 4例 ,2例死亡 ,1例脑瘫 ,1例未见明显异常 ;低电压 5例 ,1例死亡 ,1例脑瘫 ,1例 IQ低下 ,2例未见异常 ;9例节律性放电者 ,1例出现癫。EEG重度异常后遗症发生率为 2 9% ,轻度异常其发生率为 3 %。 结论 EEG异常情况与临床 HIE程度呈正相关 ,且重度异常者其后遗症发生率显著高于轻度异常者。新生儿 EEG可作为 HIE早期判断预后的一种有效、方便的检查手段。
Objective To observe the value of EEG in judging the prognosis of HIE in children with hypoxic-ischemic encephalopathy (HIE). Methods Totally 57 children with HIE were enrolled in this study. Physical examination and intelligence test were performed on the 62 children with HIE. CT and EEG were performed to evaluate the relationship between clinical sequelae and EEG during the neonatal period. Results EEG in 62 neonates with HIE during neonatal period showed that electrosurgery occurred in 3 patients, 2 patients died and 1 patient developed hemiplegia. Outbreak was inhibited in 4 patients, 2 patients died, 1 patient had cerebral palsy and 1 patient had no abnormalities. 1 patient died, 1 patient had cerebral palsy, 1 patient had low IQ, 2 patients had no abnormality; 9 patients had rhythmic discharge and 1 patient had epilepsy. The incidence of severe sequelae of EEG was 29% and mild abnormality was 3%. Conclusion The abnormality of EEG is positively correlated with the degree of clinical HIE, and the incidence of sequelae of severe abnormalities is significantly higher than that of mild abnormalities. Neonatal EEG can be used as an effective early detection of HIE prognosis, a convenient means of inspection.