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目的探讨小儿重症肺炎采用氨溴索联合小剂量肝素雾化吸入治疗的临床效果。方法选择2014年4月至2015年4月深圳市石岩人民医院收治的98例小儿重症肺炎患儿,按照随机数字表法分为观察组和对照组,每组49例。对照组给予常规治疗,观察组在常规基础上联合应用氨溴索及小剂量肝素雾化吸入治疗,比较两组患儿发热、鼻翼扇动、紫绀、三凹征、肺部啰音等体征消失时间及治疗效果。结果观察组发热、鼻翼扇动、紫绀、三凹征、肺部啰音等临床体征消失时间均明显短于对照组,差异有统计学意义(P<0.05);观察组治疗有效率为92.31%,显著优于对照组的78.85%,差异有统计学意义(P<0.05)。结论小儿重症肺炎联合应用氨溴索及小剂量肝素雾化吸入治疗,疗效显著,值得临床推广应用。
Objective To investigate the clinical effect of ambroxol combined with low-dose heparin atomized inhalation in pediatric severe pneumonia. Methods From April 2014 to April 2015, 98 children with severe pneumonia admitted to Shenzhen Shiyan People’s Hospital were divided into observation group and control group according to random number table method, with 49 cases in each group. The control group was given conventional treatment. The observation group was treated with ambroxol and low-dose heparin atomized inhalation on the basis of routine. The signs of disappearance of fever, nose fan, cyanosis, triple recess and pulmonary rales were compared between the two groups And treatment effect. Results The disappearance time of clinical signs such as fever, nasal flaps, cyanosis, triple depression and pulmonary rales in the observation group were significantly shorter than those in the control group (P <0.05). The effective rate of the observation group was 92.31% Significantly higher than 78.85% of the control group, the difference was statistically significant (P <0.05). Conclusion Severe pneumonia in children combined with ambroxol and low-dose heparin inhalation therapy, the effect is significant, worthy of clinical application.