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评价肺部磨玻璃样改变的高分辨率ＣＴ（ＨＲＣＴ）检查、病理基础以及它在弥漫性肺疾病（ＤＰＤ）中的诊断价值。材料和方法：一组连续的经病理学检查或临床综合其它各种检查而明确诊断的弥漫性肺疾病，经普通Ｘ线、ＣＴ和ＨＲＣＴ检查，ＨＲＣＴ采用层厚为１－１．５ｍｍ，间隔为１０ｍｍ，高空间频率重建算法。有病理学结果者则与之对照。结果：本组ＤＰＤ包括７３例，ＨＲＣＴ显示磨玻璃样改变征象１６例，分别为过敏性肺炎５例、淋巴瘤ｌ例、皮肌炎２例、特发性肺纤维化３例、类风湿性肺炎２例、放射性肺炎１例和肺水肿２例。普通Ｘ线仅显示９例（Ｐ＜０．０１）。病理学上磨玻璃样改变由肺泡腔内渗出、肺泡间隔增厚所致。结论：ＨＲＣＴ是显示肺部早期异常表现——磨玻璃样改变十分有效的方法，但对弥漫性肺疾病的鉴别诊断缺乏特异性。
To evaluate the high-resolution CT (HRCT) examination of lung-ground vitreous changes, its pathological basis and its diagnostic value in diffuse lung disease (DPD). MATERIALS AND METHODS: A series of consecutive diffuse lung diseases diagnosed by pathological examination or other comprehensive clinical examination were examined by X-ray, CT and HRCT. HRCT was performed with a layer thickness of 1-1.5 mm, 10mm, high spatial frequency reconstruction algorithm. With pathological results were compared with that. Results: There were 73 cases of DPD in this group, and 16 cases showed changes of ground glass by HRCT, including 5 cases of allergic pneumonia, 1 case of lymphoma, 2 cases of dermatomyositis, 3 cases of idiopathic pulmonary fibrosis, rheumatoid 2 cases of pneumonia, 1 case of radiation pneumonitis and 2 cases of pulmonary edema. Common X-ray showed only 9 cases (P <0.01). Pathological changes in ground glass by the alveolar exudate, alveolar septum thickening caused. CONCLUSIONS: HRCT is a very effective method to show the early abnormalities of the lungs - ground glass changes, but it lacks specificities in the differential diagnosis of diffuse lung diseases.