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目的:探讨甲氨喋呤的不同剂量、不同给药方式治疗异位妊娠的效果。方法:随机将141例患者分为3组,A组单次肌肉注射甲氨喋呤(MTX)按体表面积50mg/m2,B组分次肌肉注射甲氨喋呤0.4mg/kg.d,5日1疗程,C组单次肌肉注射甲氨喋呤50mg/m2配伍口服米非司酮600mg顿服。结果:单一用药的两组治愈率分别为76.08%、78.13%,而联合用药组治愈率为93.6%,明显高于其他两组。结论:3组方法治疗异位妊娠均有效,但联合用药组治愈率高,疗程短。
Objective: To investigate the different doses of methotrexate, different modes of treatment of ectopic pregnancy effect. Methods: A total of 141 patients were randomly divided into three groups: group A received intramuscular methotrexate (MTX) at a dose of 50 mg / m2, group B received intramuscular injection of methotrexate 0.4 mg / kg.d, Day 1 course of treatment, C group a single intramuscular injection of methotrexate 50mg / m2 oral mifepristone 600mg Dayton clothing. Results: The cure rates of the two groups were 76.08% and 78.13% respectively, while the cure rate of the combination group was 93.6%, which was significantly higher than the other two groups. Conclusion: All the three methods are effective in treating ectopic pregnancy, but the combined treatment group has high cure rate and short course of treatment.