脉络宁与常用治疗中风药钙拮抗剂尼莫地平比较，两者在降低死亡率、减轻神经系统损伤等方面疗效相近，与未治疗的模型组比较，均有显著的统计学差异（Ｐ＜０．０５或Ｐ＜０．０１）。脉络宁大剂量（３．６ｍｌ／ｋｇ）除上述作用更显著外（与模型组比较，Ｐ＜０．０１），对梗塞引起的脑水肿也有显著的消除作用（Ｐ＜０．０５）。脉络宁有显著增加动物模型血浆中６－酮－ＰＧＦ１α的含量（小、大剂量皆Ｐ＜０．０１），并能使其血浆浓度显著高于正常动物（小、大剂量皆Ｐ＜０．０５）和显著降低血浆中ＴＸＢ２的含量的作用（与模型组比较，小剂量Ｐ＜０．０５，大剂量Ｐ＜０．０１）；而尼莫地平则无明显作用 Mailuoning was compared with nimodipine, a calcium antagonist used to treat stroke, and both had similar efficacy in reducing mortality and reducing nervous system damage. Compared with the untreated model group, there were significant statistical differences (P<0). .05 or P<0.01). The high dose of Mailuoning (3.6ml/kg) was more effective than the above-mentioned effect (P<0.01 compared with the model group), and it also had a significant elimination effect on cerebral edema caused by infarction (P<0.05). Mailuoning significantly increased the content of 6-keto-PGF1α in plasma of the animal model (both small and large doses were P<0.01), and the plasma concentration was significantly higher than that of normal animals (both small and large doses were P<0. 05) and significantly lower plasma TXB2 level (compared with model group, low dose P<0.05, high dose P<0.01); while nimodipine has no significant effect