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目的:加强抗菌药物的合理应用和减少药物滥用。方法:随机抽取本院2009年1—6月行手术治疗的住院病历300份,调查不同切口类型手术围手术期预防使用抗菌药物的情况。对抗菌药物的选择、剂量、给药方法与疗程等进行合理性评价。结果:300份病历中,抗菌药物使用率92.3%,其中Ⅰ类切口使用率72.0%,Ⅱ、Ⅲ类切口使用率100%;抗菌药物不合理应用主要是选药不合理、用药方法不正确、用药疗程不合适及初次给药时间不合适,分别占10.7%、7.7%、6.0%及6.7%。结论:本院外科围手术期抗菌药物应用趋于规范,但还存在选药档次偏高、术后预防应用时间偏长等问题,需要继续加强抗菌药物使用督导工作。
Objective: To strengthen the rational use of antimicrobial agents and reduce drug abuse. Methods: A total of 300 hospitalized patients undergoing surgical treatment in our hospital from January to June in 2009 were randomly selected to investigate the prevention of the use of antimicrobial agents during perioperative period in different types of incisions. The choice of antibacterial drugs, dosage, methods of administration and treatment for reasonable evaluation. Results: In 300 medical records, the usage rate of antibacterials was 92.3%, among which the usage rate of type Ⅰ incision was 72.0% and the usage rate of type Ⅱ and type Ⅲ incision was 100%. The irrational application of antibacterial drugs was mainly because of unreasonable drug selection, incorrect medication method, Inappropriate medication courses and inappropriate initial administration time accounted for 10.7%, 7.7%, 6.0% and 6.7% respectively. CONCLUSIONS: The application of perioperative antibiotics in our hospital tends to be standardized, but there are still some problems such as the high grade of drug selection and the long time of prevention and treatment after operation. It is necessary to continue to strengthen supervision over the use of antimicrobial agents.