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目的:研究茵柏益肝汤不同配伍对急性肝损伤大鼠的肝脏保护作用。方法:用四氯化碳致大鼠急性肝损伤,以生化指标和病理变化评价茵柏益肝汤的肝脏保护作用,观察茵柏益肝汤不同配伍对急性肝损伤大鼠的肝脏保护作用。结果:全方组保肝作用最强,含茵陈的各配伍组其保肝作用均强于不含茵陈的配伍组;配伍岩柏草-凤尾草-六月雪后保肝作用增强;配伍金钱草、矮地茶后各配伍组的保肝作用没有明显变化。结论:茵陈、岩柏草-凤尾草-六月雪、金钱草、矮地茶在茵柏益肝汤中分别起到君臣佐使的作用,深刻体现了组方规律。
Objective: To study the hepatic protective effect of Yinbiyigan decoction with different compatibility on acute liver injury in rats. Methods: Acute liver injury induced by carbon tetrachloride (CCl4) was used to evaluate the hepatic protective effect of Yinbaiyi Gan Tang in rats. The hepatic protective effect of Yinbaiyi Gan Tang with different compatibility was observed. Results: The whole group had the strongest hepatoprotective effect, and the hepatoprotective effect of all compatibility groups was better than that of the non-Herba compatibility group. The compatibility of Yanbaicao-Pseudoserus in June snow increased the hepatoprotective effect ; Compatibility money grass, short tea after the compatibility group did not change the role of liver protection. Conclusion: Yinchen, Iwonii - Pteris juniper - June snow, money grass, dwarf tea in the Yin Bo Yi Gan Tang played the role of the minister respectively, a profound manifestation of the formula side of the law.