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目的研究分析100例脑血栓形成患者红细胞免疫功能和血液流变学测定及临床效果。方法回顾性分析原阳县中医院于2012年9月至2013年9月收治的100例脑血栓形成患者的病历资料,将100例脑血栓形成患者作为观察组,选取我院同一时期100例体检者作为对照组,对观察组患者和对照组健康体检者的红细胞免疫功能和血液流变学进行测定。结果脑血栓形成患者的红细胞C3b受体花环率(RBC-C3bRR)低于对照组健康体检者,差异有统计学意义(P<0.05);观察组患者的红细胞免疫复合物花环率(RBC-ICR)高于对照组,差异有统计学意义(P<0.05)。两组的全血黏度高切、全血黏度低切、血浆黏度、血沉、血沉方程K值以及纤维蛋白原比较差异有统计学意义(P<0.05),两组红细胞压积指标比较差异未见统计学意义(P>0.05)。高血压是其最主要的危险影响因素,其次是冠心病和吸烟。结论脑血栓形成患者最主要的影响因素不仅取决于红细胞免疫功能的紊乱,也取决于血液流变学特性的异常。
Objective To study the erythrocyte immune function and hemorheology in 100 patients with cerebral thrombosis and its clinical effect. Methods The clinical data of 100 cases of cerebral thrombosis patients who were treated in Yuanyang Hospital of Traditional Chinese Medicine from September 2012 to September 2013 were retrospectively analyzed. 100 cases of cerebral thrombosis were selected as the observation group, and 100 cases of physical examination As a control group, the observation group patients and control subjects healthy subjects were detected erythrocyte immune function and hemorheology. Results The RBC-C3bRR of patients with cerebral thrombosis was significantly lower than that of healthy controls (P <0.05). The RBC-ICR ) Higher than the control group, the difference was statistically significant (P <0.05). The two groups of high blood viscosity, low blood viscosity, plasma viscosity, ESR, K value and fibrinogen were significantly different (P <0.05) Statistical significance (P> 0.05). Hypertension is the most important risk factor, followed by coronary heart disease and smoking. Conclusion The most important influencing factors in patients with cerebral thrombosis depend not only on the disorder of erythrocyte immune function but also on the abnormality of hemorheology.