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Discovery of a Novel NO-Donating Bifendate Derivative with Promising Action against both Drug-Suscep
[会议论文] 作者：Yihua Zhang,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
Multidrug resistance(MDR) is a major obstacle to successful cancer chemotherapy,and novel biologically based treatment strategies that can overcome MDR are urgently needed.1,2 In this study,a series o...
[期刊论文] 作者：Fang LI,Yihua ZHANG,,
来源：Chinese Journal of Library and Information Science 年份：2012
Purpose:This study aims to discuss the strategies for mapping from Dewey Decimal Classification(DDC)numbers to Chinese Library Classification(CLC)numbers based...
[会议论文] 作者：Chun Han,Yihua Zhang,
来源：第十一届华北地区五省市化学学术研讨会 年份：2015
A series of hybrids from phenylsulfonylfuroxan and anilinopyrimidine were synthesized and biologically evaluated as EGFR inhibitors for intervention of NSCL...
Hybrids of Phenylsulfonylfuroxan and Anilinopyrimidine:Synthesis and Biological Evaluation as Potent
[会议论文] 作者：Chun Han,Yihua Zhang,
来源：第十一届华北地区五省市化学学术研讨会 年份：2015
A series of hybrids from phenylsulfonylfuroxan and anilinopyrimidine were synthesized and biologically evaluated as EGFR inhibitors for intervention of NSCL...
Cloning the Promoter of BcNA1 from Brassica napus and Fad2 Gene from Arabidopsis thaliana and Constr
[期刊论文] 作者：Shi Dongqiao,Zhou Yihua,Zhang,
来源：高技术通讯（英文版） 年份：2004
The upstream regulatory region of a seed-specific gene was isolated from the genomic DNA of Brassica napus by PCR amplification. The cloned fragment contained 1...
Discovery of Novel Monocarbonyl Ligustrazine-Curcumin Hybrids as Potential Thioredoxin Reductase Inh
[会议论文] 作者：Zhangjian HUANG,Yong AI,Yihua ZHANG,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
The elevation of oxidative stress preferentially in cancer cells by inhibiting thioredoxin reductase(TrxR)and/or enhancing reactive oxygen species(ROS)has emerged as an effective strategy for selectiv...
[会议论文] 作者：Chun HAN,Sixun PENG,Yihua ZHANG,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Irreversible EGFR inhibitors can overcome the EGFRT790M-relatedresistance.[1,2]Novel compounds 12a-i were synthesized and biologically evaluated....
[会议论文] 作者：Jianbing Wu,Yihua Zhang,Zhangjian Huang,
来源：2016年长三角药物化学研讨会 年份：2016
Evidence is accumulating that high levels of nitric oxide (NO) could act as a cytotoxic and apoptosis-inducing agent against tumor cells.[1]Diazeniumdiolates derived from secondary amines usually act...
FIRST SYNTHESISOF 12-OXOSOLADUCIDINE AND ITS DERIVATIVES AS POTENTIAL ANTI-TUMOR STEROIDAL ALKALOIDS
[会议论文] 作者：Xiaoming Zha,Yingwei Hou,Hongbin Sun,Yihua Zhang,
来源：第67届世界药学大会(67th International Conference of FIP) 年份：2007
...
[会议论文] 作者：Chun Han,Hongbin Ji,Sixun Peng,Yihua Zhang,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
The EGFR T790M mutant contributes approximately 50% to clinically acquired resistance against gefitinib or erlotinib.Irreversible EGFR inhibitors can overcome the EGFR T790M-related resistance.1,2 The...
[会议论文] 作者：Jingchao LIU,Wenlong LI,Zhangjian HUANG,Sixun PENG,Yihua ZHANG,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Rosiglitazone is clinically used to treat insulin resistance.However,its long-term administration will increase the incidence of cardiovascular side effects.[1] Given the beneficial effects of nitric...
Synthesis and Biological Evaluation of GST-π-Based Novel NO-Donating CDDO Derivatives as Potential A
[会议论文] 作者：Fenghua KANG,Yong AI,Zhangjian HUANG,Sixun PENG,Yihua ZHANG,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
...
Design,Synthesis and Biological Evaluation of Nitric oxide/Hydrogen Sulfide-Donating Hybrids of 3-n-
[会议论文] 作者：Wei YIN,Jiangen FANG,Zhangjian HUANG,Sixun PENG,Yihua ZHANG,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
...
Identification of Nitric Oxide-Releasing Derivatives of Oleanolic Acid as Potential Anti-Colon Cance
[会议论文] 作者：Yu ZOU,Junjie FU,Zhangjian HUANG,Huibin ZHANG,and Yihua ZHANG,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
The overexpressed GSTπ isozyme in tumor cells was regarded as targets for the design of anti-cancer agents.Herein,a group of GSTπ-based nitric oxide(NO)-releasing derivatives of oleanolic acid(OA)(1–9...
Design and synthesis of novel piperlongumine derivatives for intervention of colon cells proliferati
[会议论文] 作者：Yu Zou,Chang Yan,Zhangjian Huang,Huibin Zhang,Yihua Zhang,
来源：2016年长三角药物化学研讨会 年份：2016
...
[会议论文] 作者：Jing Wu,Jingjing Ling,Hui Ji,Sixun Peng,Yihua Zhang,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
The development of novel anti-thrombotic agents with strong free radical scavenging activity is of great significance for the treatment of ischemic stroke.1 In the present study,3-alkyl/arylalkyl-subs...
Cloning the Promoter of BcNA1 from Brassica napus and Fad2 Gene from Arabidopsis thaliana and Constr
[期刊论文] 作者：Shi Dongqiao,Zhou Yihua,Zhang Lihua,Liu Guizhen,Zhang Tiehan,Chen Zhenghua,
来源：黑龙江科技信息 年份：2000
本文通过对荣华二采区10...
[会议论文] 作者：Jianhu XIAO,Yi ZOU,Minghao LUO,Jian ZHUANG,Yihua ZHANG,Yisheng LAI,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Brutions tyrosine kinase(BTK)is a key component of the B-cell receptor signaling pathway which plays a critical role in B-cell development.Ample evidence indicates that the dysregulation of BTK is ass...
Discovery of Novel NO-donating Bifendate Derivatives as Potential Anti-tumor Agents Against Aultidru
[会议论文] 作者：Xiaoke Gu,Xiaobo Tang,Hui Peng,Yisheng Lai,Sixun Peng,Yihua Zhang,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
Multidrug resistance (MDR) is a major obstacle to successful cancer chemotherapy,and novel strategy is urgently required to improve the efficacy of chemotherapeutic agents against MDR.1-3 In this stud...
Suspension culture efficiently induced bone marrow mesenchymal stem cells to differentiate into func
[会议论文] 作者：Yihua Zhang,Wenzheng Shen,Anmin Lei,Jinlian Hua,Huayan Wang,Zhongying Dou,
来源：中国畜牧兽医学会第三届中国兽医临床大会 年份：2012
Bone marrow mesenchymal stem cells (BMSCs) have shown the properties of immunosuppression and low immunogenicity and the potential capacity for differentiating into pancreatic islet-like cell clusters...
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