Antisense相关论文
33. The Study of Mechanism By Which The Telomerase Template Phosphorothioate Antisense Oligonucleoti
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30. Knockdown of IGF-IR by Antisense Oligodeoxynucleotide auguments the sensitivity of bladder cance
AND AIM: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western popu......
22. Proteomic Analysis of Differential Protein Expression in vero Cell with Antisense Blocking of Re
Objective: Recent studies have demonstrated that cells exposed to ionizing radiation or alkylating agents can develop pr......
遗传性视网膜变性在临床上缺乏有效的治疗手段，基因治疗有望从根本上恢复遗传物质的功能，为其提供新的治疗策略。反义寡核苷酸(AON)......
Antiviral effect of antisense oligodeoxynucleotides complementary to hepatitis B virus X gene in vit
Objective To investigate the antiviral effect of antisense phosphorothioate oligodeoxynucleotides （ASODNs） complementary t......
Co-transfection of MRP and bcl-2 antisense S-oligodeoxynucleotides reduces drug resistance in cispla
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Reversing drug resistance in the ovarian carcinoma cell line SKOV3/mdr1 in vitro by antisense oligod
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<span style=“font-family:”“><span style=”font-family:Verdana;“>For just about 30 years, researchers have considered......
<em>Background:</em> Antisense peptide nucleic acids (PNAs) exhibit growth inhibitory effects on bacteria by inhibiting ......
Discovering multiple transcripts of human hepatocytes using massively parallel signature sequencing(
Background: The liver is the largest human internal organ-it is composed of multiple cell types and plays a vital ro......
Objective: To evaluate the inhibitory effects of PIN1 antisense gene on the proliferation of human osteosarcoma cells. M......
Objective:To study the effects of antisense PTEN gene on the growth and invasion of glioma cells. Methods: A pcDNA3. 1/H......
The inhibitory effects of siRNA expression vector on CXCR4 expression in prostate carcinoma cell lin
Objective: To investigate the inhibitory effects of RNAi (RNA interference, RNAi) expression vector on CXCR4 expression ......
目的 寻找抗ＨＢＶ最佳反义寡核苷酸区段。方法 合成４种互补于ＨＢＶ不同区段的反义硫代寡核酸（ａｓＯＮ），加入ＨＢＶ基因转染的肝癌细胞模型ＨｅｐＧ２２．２．１５，以ＥＬＳＡ法测定ＨＢｓＡｇ、ＨＢｅＡｇ含量。结......
Among the expressed sequence tags (ESTs) which were isolated from genetically instable monkey kidney vero cells induced ......
RETROVIRUS MEDIATED TRANSFER OF ANTISENSE HUMAN c-myc GENE INTO HUMAN ESOPHAGEAL CANCER CELLS SUPPRE
A retroviral vector, called pDAM3, containing the neomycin resistant gene and the antisense human c-myc gene fragment (t......
To overcome ampicillin-resistance of bacteria which is believed to attribute their endogenous β-lactamase,we designed t......
Different Patterns of Cyclin D1/CDK4-E2F-1/4 Pathways in Human Embryo Lung Fibroblasts Treated by Be
Objective To investigate the roles of the cyclin D1/CDK4 and E2F-1/4 pathways and compare their work patterns in cell cy......
Background Insulin-like growth factor binding protein-1 (IGFBP-1), which is a carrier of Insulin-like growth factors (I......
THE LOCALIZATION OF ADRENOMEDULLIN IN RAT KIDNEY TISSUE AND ITS INHIBITORY EFFECT ON THE GROWTH OF C
Adrenomedullin（AM），anovelhypotensivepeptideoriginallyisolatedfromhumanpheochromocytoma（１），wassynthesizedinvarioustissues（２，３）．Thecalc......
COMPARATIVE STUDY OF FIBRONECTIN GENE EXPRESSION IN TISSUES FROM HYPERTROPHIC SCARS AND DIABETIC FOO
Objective.To explore the expression characteristic of fibronectin gene in hypertr ophic scars and diabetic ul-cer tissue......
AIM: To detect the resistin expression of white adipose tissue in diet-induced obese (DIO) versus diet-resistant (DR)ra......
Glomerular hypertrophy and progressive expansion of extracelluar matrix (ECM) have been regarded as the early feature of......
Hematopoiesis is an active process of cell proliferation, differentiation and release. It is the process during which he......
Inhibiting effect of vascular endothelial growth factor (VEGF) antisense oligodeoxynucleotides on VE
Objective:To study the effect of VEGF antisense oligodeoxynucleotide(VEGF ASODN)on VEGF expression in acute monocyte leu......
Recombinant adeno-associated virus-mediated delivery of antisense angiotensin Ⅱ receptor 1 gene atte
Aim:The renin-angiotensin system plays a crucial role in the development andestablishment of hypertension,and the pharm......
ROLE OF ANTISENSE AND DECOY OLIGONUCLEOTIDE OF NF-κB IN VESSEL STENOSIS AND NEOINTIMA FORMATION IN B
Objective To examine antisense and decoy oligonucleotides of nuclear factor kappa B in vivo effects on intima proliferat......
Objectives To study the depressive effect of the antisense oligonuceotides (ASODN) of c-myc and proliferating cell nucle......
Focal adhesion kinase antisense oligodeoxynucleotides inhibit human pulmonary artery smooth muscle c
Background Pulmonary artery smooth muscle cell (PASMC) proliferation plays an important role in pulmonary vessel struct......
Obejctive To detect the influence of antisense s oligodeoxynucleotides (S ODNs) of bd 2 and multidrug resistamce......
AIM:To investigate the effect of antisense RNA to vascularendothelial growth factor_(165)(VEGF_(165))on human esophagea......
Objective: To explore the role of vascular endothelial growth factor (VEGF) in the angiogenesis and development of human......
AIM:To investigate the role of TR3 in induction of apoptosisin gastric cancer cells.METHODS:Human gastric cancer cell l......
AIM:Esophageal carcinoma is one of the most commonmalignant tumors in China.But the molecular mechanismsof esophageal c......
Objectives: To clarify the inhibition of pancreatic can-cer cells by interference with the hTR component of thetelomera......
Effect of antisense oligonucleotides targeting telomerase catalytic subunit on tumor cell proliferat
To screen specific antitumor drugs targeting telomerase catalytic subunit (hEST2), 12 different hEST2 antisense oligonuc......
Relationship between telomerase activity and its subunit expression and inhibitory effect of antisen
AIM:To directly investigate the relationship betweentelomerase activity and its subunit expression and the inhibitoryef......
AIM:To investigate the anti-tumor mechanism of antisenseoligodeoxynucleotide cantide against hTERT.METHODS:Tumor cells ......
Inhibitory effects of antisense RNA of HAb18G/CD147 on invasion of hepatocellular carcinoma cells in
AIM:To study the inhibitory effects of antisense RNA ofHAb18G/CD147 on invasion of hepatocellular carcinoma(HCC)cells i......
Telomerase activity and cell apoptosis in colon cancer cell by human telomerase reverse transcriptas
AIM:To evaluate the effect of human telomerase reversetranscriptase(hTERT)gene antisense oligodeoxynucleotide(As-ODN)on......
AIM TO construct a novel HBV antisense RNA deliverysystem targeting hapatocellular carcinoma and study itsinhibitory eff......
AIM:To investigate the expression level of ZNRD1 gene ingastric cancer cells SGC7901 and gastric cancer MDR(multidrug r......
Summary:To construct the antisense transforming growth factorβ1(TGFβ1)gene and investigatethe effect of TGFβ1 autocr......
Contribution of elF-4E inhibition to the expression and activity of heparanase in human colon adenoc
AIM:Heparanase degrades heparan sulfate proteoglycans(HSPGs) and is a critical mediator of tumor metastasis andangiogen......
AIM:To understand the response of human REV3gene togastric cancer inducing carcinogen N-methyI-N’nitro-N-nitrosoguanid......
