EPITOPE相关论文
Molecularly imprinted polymers (MIPs),as important mimics of antibodies,are chemically synthesized by polymerization in ......
Characterization of two monoclonal antibodies, 38F10 and 44D11,against the major envelope fusion pro
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Highly pathogenic avian influenza A virus H5N1 continues to spread among poultry and has frequently broken the species b......
A novel monoclonal antibody,CC4,targeting a conserved epitope of CEACAMs significantly inhibits tumo
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Dysfunctional Characteristics of antibody-dependent cellular cytotoxicity mediated by CD56+Natural K
Objective:As an important cooperated immune response of innate and adaptive immunity,CD56+ NK cell-mediated antibody-dep......
The induction of antigen specific memory CD8+ T cells in vivo is very important to new vaccines against infectious disea......
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Identification of an HLA-A*0201-Restricted CTL epitopic peptide from human RA associated main autoan
Objective:collagen Ⅱ has emerged in recent years as amajor antigen in human RA.A specific CD4+ T cell response to pepti......
Fabrication of Epitope Imprinted Polyethersulfone Particles through Self-assembly for Protein Recogn
Molecular imprinting is a technology in which specific recognition sites are formed in a polymer matrix by synthesis in ......
To achieve the simultaneous capture of various target proteins,the multi-epitope templates imprinted particles were ......
The study of protein structures and functions is very important for the development of proteomics.Current protein analys......
Objective: To explore the impact of V5-epitope tag inserted in the commercial pcDNA5/FRT/V5-His TOPO expression vector o......
目前,我国南非Ⅱ型（SATⅡ）口蹄疫病毒（FMDV）的防控形势十分严峻,为了防止SATⅡ型FMD的跨境传入,迫切需要建立其特异的检测方法。本研究......
为了制备小反刍兽疫病毒（PPRV）特异性单抗及临床抗体水平监测,通过在线软件分析PPRV Nigeria75/1株M蛋白可能包含的B细胞线性表位位......
通过全化学法按大肠杆菌密码偏性合成了乙肝炎病毒前Ｓ２抗原抗原决定簇基因，与霍乱毒素Ｂ亚基基因的３＇端融合，重组质粒转化大肠杆菌后融合基......
In the MHC classⅠmolecule binding antigenic peptides processing and presentation pathway,the ubiquitin-proteasome syste......
类风湿性关节炎(RA)与许多免疫系统慢性疾病一样,很可能起因于遗传易感性与环境触发因素的结合。来自于瑞典的一个研究小组近日开......
目的对抗原编码基因esxA、fbpB、Rv2660c进行测序,了解esxA、fbpB、Rv2660c的基因多态性。方法选取135株结核分枝杆菌(Mycobacteri......
Conserved regions of Plasmodium vivax potential vaccine candidate antigens in Sri Lanka:Conscious in
Objective:To do mapping and modeling of conformational B cell epitope regions of highly conserved and protective regions......
N-terminal residues of an HIV-1 gp41 membrane-proximal external region antigen influence broadly neu
The Human immunodeficiency virus type 1(HIV-1) gp41 membrane proximal external region(MPER) is targeted by broadly neutr......
Combinatorial peptide libraries have become powerful tools to screen functional ligands by the principle of affinity sel......
Development of an oral DNA vaccine against MG7-Ag of gastric cancer using attenuated salmonella typh
AIM:To develop an oral DNA vaccine against gastric cancerand evaluate its efficacy in mice.METHODS:The genes of the MG7......
Objective: With the development of peptide-based cancer specific immunotherapy, the prediction of CTL epitopes from insu......
HIV-1 p24 detection provides a means to aid the early diagnosis of HIV-1 infection, track the progression of disease and......
Preparation and Identification of HLA-A*1101 Tetramer Loading with Human Cytomegalovirus pp65 Antige
MHC/peptide tetramer technology has been widely used to study antigen-specific T cells, especially for identifying virus......
Computational Prediction and Identification of Epstein-Barr Virus Latent Membrane Protein 2A Antigen
Epstein-Barr virus (EBV) associated nasopharyngeal carcinoma (NPC) is a high incidence tumor in Southeast Asia. Among EB......
Phage displaying peptides mimic schistosoma antigenic epitopes selected by rat natural antibodies an
AIM: To obtain the short peptides mimic antigenic epitopes selected by rat natural antibodies to schistosomes, and to ex......
Prediction of HLA-A2-restricted CTL epitope specific to HCC by SYFPEITHI combined with polynomial me
AIM: To predict the HLA-A2-restricted CTL epitopes of tumor antigens associated with hepatocellular carcinoma (HCC).METH......
Objective:To explore a common B- and T- cell epitope-based vaccine that can elicit an immune response against encephalit......
Serial Expression of the Truncated Fragments of the Nucleocapsid Protein of CCHFV and Identification
The Crimean-congo hemorrhagic fever virus(CCHFV)is a geographically widespread fatal pathogen.Identification of the epit......
In recent years, the in silico epitopes prediction tools have facilitated the progress of vaccines development significa......
PD-1 plays an important role as an immune checkpoint.Sintilimab is a newly approved PD-1 antibody for cancer immunothera......
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused a worldwide severe coronavirus disease 2019(COVID-......
Identification and Characterization of Peptides Mimicking the Epitopes of Metalloprotease of Schisto
In an attempt to isolate and characterize peptides mimicking epitopes of metalloprotease and explore their immunological......
Objective To study the polymorphism in P66 and its human B-cell epitopes of Borrelia burgdorferi strains in China.Method......
The objective of this study was to characterize the oxygen dependent regulation of pyruvate oxidase (SpxB) gene expressi......
最新研究发现,开发艾滋病病毒(HIV)疫苗可能比想象中更加困难。因为HIV不仅会对抗病毒药产生抗性,而且会进化产生规避人类免疫系统......
Objective Four B and Th cell epitopes were selected from conservative domain of Plasmodium falciparum antigens to const......
Objective To construct and evaluate a recombinant multi epitope, multistage malaria vaccine candidate expressed in ......
AIM: To determine whether dendritic cells (DCs) fromchronic hepatitis B patients could induce HBV antigen-specific T ce......
The global epidemic of HIV infection, the cause ofAIDS, has created an urgent need for novel classes ofantiretroviral ag......
Therapeutic polypeptides based on HBV core 18-27 epitope can induce CD_8~+ CTL-mediated cytotoxicity
AIM:To explore how to improve the immunogenicity ofHBcAg CTL epitope based polypeptides and to trigger anHBV-specific H......
Immune Responses to Six Synthetic Peptides of Capsid Protein with Sera from HIV-1 Infected Individua
Many B cell epitopes within p24 of human immunodeficiency virus type 1 (HIV-1) were identified,while most ofthem were d......
