Epithelial-Mesenchymal相关论文
Pancreatic cancer(PC)is the seventh leading cause of cancer death worldwide.The vast majority of patients who have PC de......
Palladium nanoplates scotch breast cancer lung metastasis by constraining epithelial-mesenchymal tra
Metastasis accounts for the majority of cancer deaths in many tumor types including breast cancer.Epithelial-mesenchymal......
Inhibition of TGF-β2-induced migration and epithelial-mesenchymal transition in ARPE-19 by sulforaph
AIM: To investigate the effects of sulforaphane(SFN) on transforming growth factor(TGF)-β2 stimulated migration and epi......
Zeb2 regulates the increase of astrocytes and recovery of motor function after spinal cord injury in
Objective:Explore the effect of Zeb2 gene on spinal cord injury(SCI)in mice and its possible mechanism.Methods:Thirty-si......
目的 探讨抑制α-catulin基因表达对胃癌细胞增殖、迁移和侵袭的影响,以及可能的机制.方法培养人胃癌细胞SGC-7901,根据转染物不同......
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophage
Objective: Solute carrier family 38 (SLC38s) transporters play important roles in amino acid transportation and signalin......
目的观察肺瘤平膏含药血清对A549细胞与巨噬细胞共培养条件下上皮间质转化(epithelialmesenchymal transition,EMT)相关mRNA及蛋白......
目的探讨N-乙酰半胱氨酸(N-Acetyl-cysteine, NAC)在百草枯(paraquat, PQ)诱导人非小细胞肺癌细胞(A549细胞)发生上皮间充质细胞转分化(ep......
肺纤维化(pulmonary fibrosis,PF)是多种间质性肺疾病的共同结果.也是引起慢性呼吸衰竭的重要原因之一.近年研究发现纤维化病灶内......
牙齿发育是一个长期、连续、复杂的生物学过程,多种信号分子参与调节,其分子机制可总结为:通过外胚层来源的上皮和下方间充质互相作用......
目的研究miRNA-183-5p在乳腺癌患者体内的表达情况及对乳腺细胞上皮间质转化的影响。方法采用Real-timePCR检测93例乳腺癌患者的乳......
目的研究TGFβ1/ILK(转化生长因子-β1/整合素连接激酶)通路在人白蛋白诱导的人近端肾小管上皮细胞(HK-2细胞)转分化过程中的作用,探讨......
目的探讨辐射诱导的miR-1246对宫颈癌He La细胞上皮间质转化(EMT)的作用。方法经不同剂量60钴(60Co)γ射线辐射处理的宫颈癌He La细胞,......
目的探讨胆汁性肝纤维化时胆管上皮细胞发生间质表型转变的特点。方法制作胆管结扎所致大鼠肝纤维化模型,利用HE染色、免疫组化和......
目的探讨微小RNA-146b(miR-146b)靶向调控人抗原R(HuR)表达及对甲状腺癌细胞上皮间质转化(EMT)的影响。方法采用实时定量PCR(QPCR)......
FBW7 increases chemosensitivity in hepatocellular carcinoma cells through suppression of epithelial-
BACKGROUND: FBW7 is a tumor suppressor which regulates a network of proteins with central roles in cell division, cell g......
Background: Epithelial-mesenchymal transition (EMT) plays an important role in pancreatic cancer (PC). In the present st......
目的探讨醉茄素-A(WFA)对肺鳞癌细胞上皮间质转化(上皮标志物E—cadherin和间质标志物Vimentin的表达)的影响,以及Notch受体拮抗剂对肺鳞......
目的:探讨姜黄素对肝细胞生长因子诱导前列腺癌DU145细胞上皮细胞间质化的影响及可能机制。方法:将DU145细胞分为3组:正常对照组、HGF......
AIM: To investigate the significance of Twist2 for colorectal cancer (CRC). METHODS: In this study, 93 CRC patients were......
Interference of suppressor of cytokine signaling 3 promotes epithelial-mesenchymal transition in MHC
AIM:To investigate the role of suppressor of cytokine signaling 3 (SOCS3) silencing in epithelial-mesenchymal transition......
AIM:To investigate the function of Pea3 in colorectal carcinoma(CRC)invasion and metastatic potential.METHODS:The expres......
AIM:To evaluate the anti-tumor effect of clobenpropit,which is a specific H3 antagonist and H4 agonist,in combination wi......
Gastric cancer is one of the most common malignant tumors worldwide.Due to its intricate initiation and progression mech......
AIM:To explore the epithelial-mesenchymal transition(EMT)in tissue from patients with Lynch syndrome,and to interpret bi......
Systematic review of the old and new concepts in the epithelial-mesenchymal transition of colorectal
Epithelial-to-mesenchymal transition(EMT) is defined as the transformation of an epithelial cell into a spindle cell wit......
Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-
AIM: To investigate the effect of integrin-linked kinase(ILK) on proliferation, metastasis, and invasion of the colorect......
目的 探讨miR-590在胆管癌细胞上皮间充质转化(EMT)中的作用及可能机制。方法 采用荧光定量PCR(QPCR)检测人正常肝内胆管上皮细胞系H......
Effect of WNT5A on epithelial-mesenchymal transition and its correlation with tumor invasion and met
Objective:To investigate the correlation between nasopharyngeal carcinoma cell WNT5A and epithelial-mesenchytnal transit......
AIM To investigate the genes regulated in mesenchymalstem cells (MSCs) and diffuse-type gastric cancer (GC),gene expression ......
AIM To investigate β-catenin (CTNNB1) signaling in cancer and stem cells, the gene expression and pathway were analyzed......
Liver injuries are repaired by fibrosis and regeneration.The cause of fibrosis and diminished regeneration,especially in......
目的:探讨α6整合素(integrin α6,ITGA6)在结直肠癌(colorectal cancer,CRC)中的表达及其对迁移与侵袭的影响。方法:使用生物信息分析ITGA......
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MicroRNA-22 (miR-22), a short non-coding RNA that post-transcriptionally regulates mRNA stability and protein synthesis,......
Differential Expression of Genes Involved in Cell Polarity, EMT and Cell-Fate in Breast Cancer and C
Objectives: Cell polarity and epithelial morphology are peculiar features of cells forming the terminal ductal lobular u......
目的探讨姜黄素对电离辐射诱导的非小细胞肺癌A549细胞上皮间质转化的影响。方法用电离辐射诱导A549细胞发生上皮间质转化,将其命......
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PRIMARY pulmonary sarcomatoid carcinoma (PSC)is a rare condition, approximately accounting for0.1%-0.4% of all lung malign......
Silencing Neuropilin 1 gene reverses TGF-β1-induced epithelial mesenchymal transition in HGC-27 gast
Objective The aim of this study was to determine Neuropilin 1(NRP1)contribution to transforming growth factorβ1(TGF-β1......
Defect of SLC38A3 promotes epithelial-mesenchymal transition and predicts poor prognosis in esophage
Objective: Solute carrier family 38(SLC38 s) transporters play important roles in amino acid transportation and signalin......
Recent research has shown that the alteration of combinations in gene expression contributes to cellular phenotypic chan......
Objective:Metastasis is one of the key causes of high mortality in lung cancer.Aberrant DNA methylation is a common even......
BACKGROUND Calponin 3(CNN3)is an actin-binding protein expressed in smooth muscle and non-smooth muscle cells.It is requ......
AIM:To evaluate the prognostic value of high-mobility group box 1(HMGB1) expression in intrahepatic cholangiocarcinoma(I......
Proteinase-activated receptor 2 promotes tumor cell proliferation and metastasis by inducing epithel
AIM To clarify the role of proteinase-activated receptor 2(PAR2)in hepatocellular carcinoma,especially in the process of......
MicroRNAs(miRNAs)are evolutionarily conserved small non-coding RNAs that affect posttranscriptional regulation by bindin......
Combination of Evodiamine with Berberine Reveals a Regulatory Effect on the Phenotypic Transition of
Objective Transdifferentiation exists between stromal cells or between stromal cells and cancer cells.Evodiamine and ber......
Assessment of the oxidative stress damage of human retinal pigment epithelium and epithelial-mesench
Objective:To study the effect of high glucose environment on oxidative stress injury of human retinal pigment epithelium......
Effect of Twist, Snail and YB-1 gene expression in cervical cancer tissue on cell invasion and epith
Objective:To study the effect of Twist, Snail and YB-1 gene expression in cervical cancer tissue on cell invasion and ep......