Temozolomide相关论文
目的 研究探讨对于脑胶质瘤患者进行替莫唑胺化疗与HOXB9 基因以及多重耐药相关分子和耐药分子的相关表达情况的相关性?方法选取我......
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Long-term Administration of Adjuvant Temozolomide Impacts Serum Potassium Concentration in Adult Pat
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目的 探讨Temozolomide(TMZ)和Bevacizumab(BEV)对裸小鼠原位胶质母细胞瘤微血管新生方式及DCE-MRI特征的影响，为胶质母细胞瘤抗血......
Temozolomidecombinedwithwholebrainradiotherapyinnon-smallcelllungcancerpatientswithbrai
目的 Theaimofthepresentmeta-analysisistoevaluatetheefficacyandsafetyofTemozolomidecombinedwithwholebrainradiotherapyvers......
LINC01094 drives the progression of diffuse gliomas and affects the sensitivity of temozolomide trea
Objective Diffuse gliomas are the most common type of primary brain tumors in central nervous system(CNS),according to t......
Entinostat-attenuated DNA repair protein MGMT plays a crucially synergistic role in temozolomide-inj
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MEK2 is a prognostic marker and potential chemo-sensitizing target for glioma patients undergoing te
Objective While temozolomide is the first-line chemotherapeutic agent against glioblastoma,its oftennon-curative due to ......
TMZ(temozolomide)treatment,as first-line chemotherapy in GBM(glioblastma),faced with drug resistance.Recent studies emph......
The study aimed to explore the specific function and mechanism of miR-144-3p in glioblastoma (GBM) cells with different ......
Fractionated Stereotactic Radiotherapy Combined with Temozolomide for Refractory Brain Metastases: A
Objective: A prospective phase Ⅱ trial was conducted to investigate the feasibility and safety of fractionated stereota......
Sulforaphane enhances temozolomide-induced apoptosis because of down-regulation of miR-21 via Wnt/β-
Temozolomide (TMZ) has been widely used in the treatment of glioblastoma (GBM), although inherent or acquired resistance......
Aim: Based on the molecular and resistance mechanism of alkylating agent temozolomide (TMZ), TMZ analogss mechanism of a......
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目的:探讨来那度胺(LEN)联合替莫唑胺（TMZ）对TMZ耐药性人脑胶质母细胞瘤系U251/TR细胞增殖、侵袭、耐药性及O6-甲基鸟嘌呤-DNA甲基转......
FOXO3a(forkhead box transcription factor 3a)is involved in regulating multiple biological processes in cancer cells.BNIP......
S-1 plus temozolomide as second-line treatment for neuroendocrine carcinoma of the breast:A case rep
BACKGROUND Neuroendocrine carcinoma of the breast(NECB)is a rare type of malignant tumor.Due to the rarity of NECB,the r......
Glioma is the most common malignancy in the brain,with poor survival and often highly resistant to chemotherapy and radi......
The Predictive value of MGMT Promoter Methylation Status in Asian and Caucasian Patients with Malign
Objective: The prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter status for survival......
目的探讨替莫唑胺辅助术后序贯放疗和同期放疗治疗星形细胞瘤的临床疗效及安全性。方法选取2008年7月至2012年7月星形细胞瘤患者90......
多形胶质母细胞瘤是颅内最常见的恶性肿瘤之一,治疗疗效差.近年来,脑多形胶质母细胞瘤的综合治疗的进展主要体现在替莫唑胺同步放......
目的探讨二十碳五烯酸(EPA)对胶质瘤U87细胞替莫唑胺(TMZ)化疗敏感性的影响及其机制。方法胶质瘤U87根据不同药物干预分为：对照组、......
Objective: The aim of our study was to analyze the long-term results of rituximab combined with temozolomide in treatmen......
脑转移性肿瘤是成人最常见的颅内恶性肿瘤，治疗手段有限，传统的治疗方法主要以放射治疗为主。替莫唑胺是新一代的烷化剂，具有透过血脑......
[目的]总结恶性脑胶质瘤病人口服化疗药物替莫唑胺的护理体会.[方法]对26例患有恶性脑胶质瘤病人施行化疗前、化疗中和化疗后的护......
目的:研究替莫唑胺复方脂质体的制备工艺,并评价其体外抗肿瘤作用。方法:采用薄膜分散法制备复方脂质体,对处方进行优化;同时对脂......
目的观察放疗联合替莫唑胺与单纯放疗相比治疗高级别胶质瘤术后患者的临床疗效及副反应。方法40例经病理证实为高级别脑胶质瘤患者......
目的:临床药师通过对1例颅内胶质瘤术后化疗患者的药学服务,探讨临床药师如何对肿瘤患者进行药学监护。方法:临床药师以抗肿瘤药物......
Downregulation of SNRPG induces cell cycle arrest and sensitizes human glioblastoma cells to temozol
Objective:Temozolomide (TMZ) is commonly used for glioblastoma multiforme (GBM) chemotherapy.However,drug resistance lim......
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,siRNA targeting stathmin inhibits invasion and enhances chemotherapy sensitivity of stem cells deri
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,Silence of bFGF enhances chemosensitivity of glioma cells to temozolomide through the MAPK signal p
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多形性胶质母细胞瘤是中枢神经系统最常见的恶性肿瘤,而且在胶质瘤中恶性程度最高.替莫唑胺为治疗多形性胶质母细胞瘤的新型烷化剂......
Leveraging Metabolomics to Assess the Next Generation of Temozolomide-based Therapeutic Approaches f
Glioblastoma multiforme(GBM) is the most common adult primary tumor of the central nervous system.The current standard o......
目的观察替莫唑胺(TMZ)、尼莫地平(NIM)、O6-苄基鸟嘌呤(O6-BG)联用对脑胶质瘤细胞株的抑制作用。探讨胶质瘤耐药发生的机制,寻找......
目的:研究替莫唑胺联合放疗治疗胶质母细胞瘤的成本-效果。方法:根据临床试验(EORTC26981/22981-NCIC CE3)数据,结合我国医疗费用......
Combination therapy of long-term tumor treating fields with temozolomide and bevacizumab prolongs su
The multifocal glioblastomas (GBM) are tumors with multiple discrete areas of contrast enhancing tumors which have consi......
目的探讨高压氧(HBO)联合替莫唑胺(TMZ)对神经胶质瘤U373MG细胞凋亡的影响及其作用机制。方法U373MG细胞培养完成后分为4组：对照组(......
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Background:The radiochemotherapy regimen concomitantly employing temozolomide (TMZ) chemotherapy and radiotherapy (RT) 4......
Objective:Glioblastoma is the most common primary brain tumor in adults and one of the most lethal human tumors. It cons......
High grade gliomas are always the research focus in the field of neurosurgery due to their poor prognosis despite the cu......
Objective: The aim of our study was to analyze the long-term results of rituximab combined with temozolomide in treatmen......
Objective: This phase II study aimed at investigating the correlation between O6-methylguanine-DNA methyl-transferase (M......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 通过体内实验探讨外源性p53上调凋亡调控因子(PUMA)对人类脑胶质瘤细胞生长的影响及其增强胶质瘤细胞对替莫唑胺(TMZ)敏感性......
Objective: This phase II study aimed at investigating the correlation between O6-methylguanine-DNA methyl-transferase (M......
