myostatin相关论文
目的 探讨糖尿病肾病(DN)患者血清肌肉生长抑制素(myostatin)水平及其与血管钙化的关系。方法 选取2019年5月至2021年5月该院收治的120......
目的:长期处于微重力环境或卧床情况下,骨骼因持续无承载、无负荷、无应力刺激,会产生骨质流失、骨吸收与骨形成平衡被破坏、破骨......
半滑舌鳎(Cynoglossus semilaevis)在我国海水养殖产业中占有重要地位,因其性别二态性而备受关注,性成熟雌鱼体长和体重显著高于雄鱼......
目的:本研究旨在尝试检测Myostatin在骨关节炎软骨细胞中的表达,初步探究Myostatin在骨关节炎疾病中的功能。研究方法:我们收集了......
目的利用谷胱甘肽S-转移酶(GST)融合系统在大肠杆菌中表达纯化大鼠myostatin蛋白,采用GST-myostatin融合蛋白进行多克隆抗体的制备、......
Expression profiles of myostatin,myogenin and myosin heavy chains in skeletal muscle of two rabbit b
The purpose of the present study was to compare mRNA levels of myostatin (MSTN),myogenin (MyoG) and fiber type compositi......
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肌肉生长抑制素(myostatin,MSTN)是抑制肌肉生长和发育的重要生长调控因子.本文通过cDNA末端快速扩增法(RACE)克隆了草鱼MSTN-1全......
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Introduction Muscle tissue is the largest tissue in the body and it may directly influence whole body growth.Muscle grow......
肌肉生长抑制素(myostatin)是肌肉生长的重要抑制因子。硬骨鱼类经过其特有全基因组复制事件(fish specific genome duplication)......
杜氏肌营养不良(Duchenne muscular dystrophy,DMD)是一种严重的遗传性肌肉疾病,是由编码抗肌萎缩蛋白(dystrophin)的基因突变引起的......
Decrease in myostatin by ladder-climbing training is associated with insulin resistance in diet-indu
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Transgenic expression of grass carp follistatin 2 in blunt snout bream mediated by Tgf2 transposon r
Myostatin(MSTN),a secreted protein belonging to the TGF-β family,inhibits muscle differentiation and growth.As a co......
Genomic identification and molecular characterization of myostatin from endemic Qinghai-Tibetan plat
Our understanding of the growth mechanism of endemic fishes in high-altitude aquatic environments remains limited.Th......
The myostatin-induced E3 ubiquitin ligase RNF13 negatively regulates the proliferation of chicken my
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应用PCR—SSCP分析方法,对94头肉牛(公牛45头:西门塔尔34头,夏洛来11头;母牛49头:西门塔尔24头,夏洛来25头)的肌肉生长抑制素(MSTN)3个外显子......
针对绵羊Myostatin基因特异性序列,设计4对shRNA,并合成高表达载体。将干扰质粒和高表达载体瞬时共转染HEK293细胞,应用Real-time ......
Myostatin is a negative regulator of skeletal muscle mass. The present study cloned the 5' regulatory region of porc......
Myostatin is a member of the transforming growth factor-β(TGF-β) super-family and functions as a negative regulator of......
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肌肉生长抑制素(Myostatin,MSTN)是抑制肌细胞增殖与分化的关键基因,对骨骼肌生长发育起着负调控作用,还参与到机体脂肪沉积等其他......
目的:随着人口老龄化基数的不断增加,骨质疏松症等慢性病的发病率越来越高,同时老年人群中男女比例失衡,每年因绝经导致的骨质疏松......
作为新生代生物技术,基因编辑技术经过不断完善与改进,以其靶标特异性和广泛适用性被用于医药与畜牧生产研究中,我们实验室利用ZFN......
MicroRNAs(miRNAs)对骨骼肌发育过程中起着关键的作用。之前的研究发现miR-128在骨骼肌中高表达,但其对骨骼肌发育的调节机制尚不......
目的采用GST-myostatin融合蛋白进行多克隆抗体的制备、鉴定并进一步阐明神经损伤后腓肠肌肌萎缩过程中myostatin蛋白表达变化。方......
目的:骨骼肌卫星细胞的增殖与分化是骨骼肌的生长调控关键环节之一,在卫星细胞增殖与分化又受很多正性调控因子与负性调控因子的影......
肌肉生长抑制素(myostatin,MSTN)是动物肌肉发育和生长过程中的负调控因子,可影响动物的产肉量,近年来颇受动物遗传育种研究者......
The relationship of serum Myostatin content with lipid metabolism, insulin resistance and inflammato
Objective:Objective: To investigate the relationship of serum Myostatin content with lipid metabolism, insulin resistanc......
,Contribution of Myostatin gene polymorphisms to normal variation in lean mass, fat mass and peak BM
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,Expression of Basic Fibroblast Growth Factor Results in the Decrease of Myostatin mRNA in Murine C2
During the development and regeneration of skeletal muscle, many growth factors, such as basic fibroblast growth factor ......
Basic fibmblast growth factor (bFGF, FG F-2 ) has an inhibitory effect on the expression of the myostatin gene in murine......
,miR-30e is negatively regulated by myostatin in skeletal muscle and is functionally related to fibe
Myostatin (MSTN) negatively regulates skeletal myogenesis in which microRNAs (miRNAs) also play critical roles.Using miR......
肌肉生长抑制素(Myostatin)是一种抑制动物骨骼肌生长发育的负调控因子,在肌细胞的形成过程中有着重要的生理功能.本课题通过分子......
Duchenne型肌营养不良症(Duchenne Muscular Dystrophy,DMD)是一种X连锁隐性遗传病,以进行性四肢近端骨骼肌萎缩无力、小腿腓肠肌假......
在调节各种生物广泛细胞应答的过程中,TGFbeta超家族成员起着关键的作用。Smads蛋白是一类分布于多种组织的信号传递分子,承担着将TG......
卵泡抑素(Follistatin)是一种分泌蛋白,它可以拮抗TGF-beta(transforming growth factor,转化生长因子)超家族中几种成员的功能,包......