【摘 要】
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Background:Acute lung injury (ALI) is a severe complication of orthotopic liver transplantation (OLT) and the underlying pathogenic mechanism is unclear.Our prior clinical studies showed that the peri
【机 构】
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Department of Anesthesiology,Third Affdiated Hospital,Sun Yat-sen University,Guangzhou,Guangdong,Chi
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Background:Acute lung injury (ALI) is a severe complication of orthotopic liver transplantation (OLT) and the underlying pathogenic mechanism is unclear.Our prior clinical studies showed that the perioperative inflammatory reaction of OLT and postoperative ALl are associated with the increased expression of TLR4.We hypothesized that a TLR4-mediated inflammation response may play a critical role in ALI during OLT.
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