Characterization of Ultrahigh MW Sodium Hyaluronate by Flow Field-Flow Fractionation & Multiangl

来源 :第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会 | 被引量 : 0次 | 上传用户:liongliong490
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  Sodium Hyaluronate (NaHA), sodium salt of hyaluronic acid or hyaluronan, is water soluble polysaccharide with a range of molecular weights (MW) (105~108 Da) composed of disaccharide repeating units of D-glucuronic acid and N-acetyl-D-glucosamine.NaHA is found in synovial fluid, body tissues such as joints, the vitreous humor, and skin.These days NaHA is being utilized in cosmetics, ophthalmic surgery, the treatment of knee joint disease, and etc.Since NaHA has different applications in practice depending on molecular weight distribution, characterization of molecular sizes and structure of NaHA is important during the degradation and refinement processes to produce desired pharmaceutical applications.
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