Studies on Novel HIV-1 Protease Inhibitors with Non-peptide Scaffolding

来源 :2006中国天津世界艾滋病日科技会议 | 被引量 : 0次 | 上传用户:applebanana0204
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  Highly active antiretroviral therapy (HAART,a combination therapy of HIV reverse transcriptase and protease inhibitors),has become an effective means of controlling viral replication and disease progress in HIV-infected individuals.As important ingrelients in HAART,there is a continuous need for new anti-retroviral drugs that interfere with different targets in the HIV replication cycle because of the factors such as long-term side effects,large pillburden as well as drug resistance issues.
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