Preparation and physicochemical properties study on multiple agents of TCM loaded PLGA nanoparticles

来源 :2012年中国药物制剂大会——中国药学会药剂专业委员会年会、亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户:xb_wonder
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The final purpose of this research is finding influencing factors of multiple agents loaded nanoparticles by study of dual agents loaded nanoparticles.Oleanic acid(OA) and Gentiopicroside(GEN) were found to be effective in treating hepatitis from different mechanism.Since the poor water-solubility of OA and short half-life period of GEN,the bioavailabilities were not well.
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