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@@ Objective The aim of our study was to assess the relationship between intrarenal Doppler parameters and the histopathology of kidney biopsy in renal transplant dysfunction. Methods We retrospectively reviewed 113 consecutive patients who underwent both transplanted kidney sonography and biopsy from May 2007 to May 2009. Doppler parameters including peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive index (RI) at the interlobar artery were compared with histopathology of the kidney biopsy. According to histopathology, the 113 patients were divided into 2 groups: 1 ) interstitial fibrosis and tubular atrophy ( IF/TA ) , and vascular/glomerular sclerosis (n=79) and 2) edematous changes in glomeruli without fibrosis (n=34) . The correlations between Doppler parameters and histopathology were statistically analyzed.