In order to synthesis more efficient adsorber of heavy metal ions,the condensation reaction of CTS with salicylaldehyde (SD) to form S-CTS in ethanol using a ultrasonic liquid processor was studied and was contrasted with conventional method.The IR spectra of condensed chitosan from the two methods showed that their molecular structures were identical.The reaction conditions such as the kind of solvents,power density and irradiation time of ultrasonic,the pH condition and the reactant ratio were optimized using an orthogonal design.