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目的调查四川省松潘县藏族成人TC边缘升高、TG边缘升高、HDL-C减低和LDL-C边缘升高的分布特点,探讨成人血脂异常与心血管病危险因素和心功能的相关性。方法采用流行病学横断面的研究方法随机、分层、整群抽样问卷调查和体格检查。结果共调查18~74岁1 015名藏族成人总胆固醇边缘升高率为17.4%;甘油三酯边缘升高率为0.5%;高密度脂蛋白-胆固醇减低率为12.1%;低密度脂蛋白-胆固醇边缘升高率为7.7%。血脂异常与心血管病危险因素有关。多因素分析显示:TC边缘升高与年龄、初中文化程度、超重正相关;HDL-C减低与异常脉压、心率、IFG正相关,与农民、干部、女性负相关;LDL-C边缘升高与年龄、大学、异常脉压正相关(P<0.05),与TC正常组相比,TC边缘升高组的SI平均水平减少,SVR升高。与TG正常组相比,TG边缘升高组的CO、SI、SV平均水平升高(P<0.05)。结论四川松潘县18~74岁藏族成人中TC边缘升高、TG边缘升高、HDL-C减低和LDL-C边缘升高率较高,与心血管病危险因素有关,对血脂异常藏族成人进行健康管理具有重要的公共卫生意义。
Objective To investigate the distribution of elevated TC edge, elevated TG edge, decreased HDL-C and elevated LDL-C edge of Tibetan adults in Songpan County, Sichuan Province, and to explore the correlation between adult dyslipidemia and cardiovascular risk factors and cardiac function. Methods Randomized, stratified, cluster sampling questionnaires and physical examinations were conducted using the epidemiological cross-sectional study. Results A total of 1 015 Tibetans aged 18-74 years were enrolled in this study. The increase rate of total cholesterol was 17.4%, the rate of increase of triglyceride edge was 0.5%, the rate of high-density lipoprotein-cholesterol was 12.1%, and low-density lipoprotein- Cholesterol margin increased by 7.7%. Dyslipidemia and cardiovascular risk factors. Multivariate analysis showed that the increase of TC margin was positively correlated with age, junior high school education and overweight. The decrease of HDL-C was positively correlated with abnormal pulse pressure, heart rate and IFG, and negatively correlated with peasant, cadres and women. There was a positive correlation with age, university and abnormal pulse pressure (P <0.05). Compared with normal TC group, the average SI level and the SVR in TC edge-enhanced group decreased. Compared with the normal TG group, the average level of CO, SI, SV in the elevated edge group of TG increased (P <0.05). CONCLUSIONS: TC margins, TG margins, HDL-C declines and LDL-C marginal increases in Tibetan adults aged 18-74 years old in Songpan County, Sichuan Province are relatively high, which are related to risk factors of cardiovascular disease and are associated with dyslipidemia in Tibetan adults Health management has important public health significance.