眼表泪液病是眼科最常见的疾病 ,是指损害眼表及泪膜功能与结构的疾病 ,可引起视功能障碍甚至失明 ,眼表泪液病的根本原因与角膜缘干细胞功能缺陷或数量不足有关 ,角膜缘干细胞是角膜上皮细胞再生的来源。本文从角膜缘干细胞和眼表泪液病的概念及角膜缘干细胞培养、移植等几个方面阐述其用于眼表泪液病的治疗及进展 Ocular surface tear disease is the most common ophthalmological disease, refers to the damage to ocular surface and tear film function and structure of the disease, can cause visual dysfunction or even blindness, the root cause of ocular surface tear disease and limbal stem cell dysfunction or lack of capacity related , Limbal stem cells are the source of corneal epithelial cell regeneration. This article from the limbal stem cells and ocular surface of the concept of tears and limbal stem cell culture, transplantation, and several other aspects of their treatment for ocular surface tear disease and progress