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儿童获得性再生障碍性贫血(ＡＡ)的骨髓衰竭机制尚不清,一般认为是干细胞功能障碍和免疫介导的造血抑制。该文对两组病人治疗结果及预后进行了比较和评价。病例和方法 以伦敦某儿童医院1973～1988年确诊的ＡＡ患儿为Ａ组(ｎ=38),1989～1996年确诊的为Ｂ组(ｎ=37)。两组病...
The mechanism of bone marrow failure in children with acquired aplastic anemia (AA) is unclear and is generally considered to be stem cell dysfunction and immune-mediated suppression of hematopoiesis. This article compares and evaluates the outcomes and prognosis of two groups of patients. Cases and Methods Patients with AA diagnosed at a London Children’s Hospital from 1973 to 1988 were Group A (n = 38) and Group B (n = 37) from 1989 to 1996. Two groups of diseases ...