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目的探究盐酸氨溴索联合利巴韦林治疗小儿支气管肺炎的临床疗效。方法选取我院2015年6月-2016年3月收治的支气管肺炎小儿患者34例,随机分为观察组和对照组各17例,对照组给予患者抗感染、平喘等对症治疗;观察组在对照组的基础上给予患者盐酸氨溴索联合利巴韦林治疗,对比两组患儿临床症状改善时间、住院时间及临床疗效。结果观察组患儿显效12例,有效4例,无效1例,总有效率为94.1%;对照组患儿显效7例,有效6例,无效4例,总有效率为76.5%;两组临床疗效对比,差异具有统计学意义(P<0.05)。观察组患儿症状消失和住院时间分别为(5.2±0.6)d、(5.6±0.5)d;对照组患儿症状消失和住院时间分别为(6.9±0.8)d、(7.1±1.1)d。两组患儿临床症状消失时间和住院时间对比,差异具有统计学意义(P<0.05)。结论盐酸氨溴索联合利巴韦林治疗小儿支气管肺炎疗效确切,能够缩短患儿的治疗时间,减少患儿痛苦,值得临床推广应用。
Objective To investigate the clinical efficacy of ambroxol hydrochloride combined with ribavirin in the treatment of bronchial pneumonia in children. Methods Totally 34 children with bronchial pneumonia who were admitted to our hospital from June 2015 to March 2016 were randomly divided into observation group and control group, 17 cases in each group. Patients in control group were given anti-infection and anti-asthma treatment. Patients in the control group were treated with ambroxol hydrochloride and ribavirin, and the improvement of clinical symptoms, hospital stay and clinical efficacy were compared between the two groups. Results In observation group, 12 cases were markedly effective, 4 cases were effective, 1 case was ineffective and the total effective rate was 94.1%. In the control group, 7 cases were markedly effective, 6 cases were effective, 4 cases were ineffective and the total effective rate was 76.5% Comparison of efficacy, the difference was statistically significant (P <0.05). The symptom disappearance and hospital stay in the observation group were (5.2 ± 0.6) days and (5.6 ± 0.5) days, respectively. The symptom disappearance and hospital stay in the control group were (6.9 ± 0.8) days and (7.1 ± 1.1) days, respectively. There was significant difference between the two groups in clinical symptoms disappearance time and hospital stay (P <0.05). Conclusion Ambroxol hydrochloride combined with ribavirin treatment of children with bronchopneumonia curative effect is exact, can shorten the treatment time of children, reduce the pain of children, it is worth to clinical application.