脓毒症是造成外科重症病人死亡的主要原因。近年来的研究显示脓毒症过程中机体免疫功能的损害与树突状细胞(DC)的变化有密切关系。脓毒症过程中DC大量丢失,生成的细胞因子也发生变化,并影响患者的预后。因此,对DC的研究有助于更好地诊断和治疗脓毒症。文章就近年来脓毒症过程中DC的研究进展作一综述。 Sepsis is the leading cause of death in critically ill surgical patients. Recent studies have shown that the damage of immune function in sepsis is closely related to the changes of dendritic cells (DCs). A large number of DCs are lost during sepsis and the resulting cytokines also change and affect the patient’s prognosis. Therefore, the study of DC helps to better diagnose and treat sepsis. In this paper, the progress of DC in sepsis in recent years is reviewed.