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目的观察长春西汀与利多卡因治疗椎-基底动脉供血不足的疗效。方法将80例椎-基底动脉供血不足患者随机分为两组,常规组应用低分子右旋糖苷、丹参、舒血宁。治疗组用长春西汀20mg、2%利多卡因100mg静滴,1次/d。两组同时给予阿司匹林片75mg/d,口服,氟桂嗪胶囊5mg,2次/d,口服。观察眩晕、恶心、眼震及脑干诱发电位。结果治疗组眩晕、恶心、眼震等症状体征及脑干诱发电位均有明显改善,治愈率及总有效率明显优于对照组(P<0.01)。结论长春西汀联合利多卡因治疗椎-基底动脉供血不足在控制病情进展、促进神经功能改善方面具有良好的安全性。
Objective To observe the curative effect of vinpocetine and lidocaine on vertebrobasilar insufficiency. Methods Eighty patients with insufficiency of vertebrobasilar artery were randomly divided into two groups. The conventional group was given low molecular weight dextran, Salvia miltiorrhiza and Shuxuening. The treatment group with vinpocetine 20mg, 2% lidocaine 100mg intravenously, 1 time / d. Both groups were given aspirin 75mg / d, oral, flunarizine capsules 5mg, 2 times / d, orally. Dizziness, nausea, nystagmus and brainstem response were observed. Results The symptoms and signs of brainstem, such as dizziness, nausea and nystagmus in the treatment group were significantly improved, and the cure rate and total effective rate were significantly better than those in the control group (P <0.01). Conclusion Vinpocetine combined with lidocaine in the treatment of vertebrobasilar insufficiency has good safety in controlling the progression of the disease and promoting the improvement of neurological function.