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目的分析西安市灞桥区病毒性甲型肝炎(甲肝)动态变化趋势、流行和影响因素。方法对来自1990-2006年疫情资料做描述流行病学分析。结果17年报告甲肝2146例,占病毒性肝炎18.29%(P<0.001);1990-1992年发病率波动在72.4/10万～94.7/10万(均数84.2/10万),1993-1999年呈明显下降趋势,发病率波动在10.5/10万～45.3/10万之间(均数34.82/10万),2000-2006年发病率维持在2.1/10万～15.1/10万之间(均数6.79/10万),游程检验下降差异有统计学意义(I=14,P<0.01),与全国发病率相比呈高度正相关(rs=0.88623,P<0.01)。17年可见间隔4～5年的4个周期(P<0.01),不同年代季节、年龄(0～、20～、30～、40～岁)、性比、职业构成差异均有统计学意义(P<0.001)。结论发病已属低流行,学校和托幼机构仍是控制重点。
Objective To analyze the dynamic changes, prevalence and influencing factors of hepatitis A (hepatitis A) in Baqiao District in Xi’an. Methods The epidemiological data from 1990 to 2006 were used to describe the epidemiological analysis. Results A total of 2146 cases of hepatitis A were reported in 17 years, accounting for 18.29% (P <0.001) of viral hepatitis. The incidence fluctuated between 72.4 / 100000 and 94.7 / 100000 in 1990-1992 (mean 84.2 / 100000), 1993-1999 Showed a significant downward trend, the incidence of fluctuations in the 10.5 / 100,000 to 45.3 / 100,000 (average 34.82 / 100,000), 2000-2006 the incidence remained at 2.1 / 100,000 to 15.1 / 100,000 (both (6.79 / 100000). There was a statistically significant difference in run test (I = 14, P <0.01), which was positively correlated with the national incidence (rs = 0.88623, P <0.01). 17 years can be seen in 4 cycles of 4 ~ 5 years intervals (P <0.01), and there are significant differences in sex, occupational composition in different age seasons, ages (0 ~, 20 ~, 30 ~, 40 ~ P <0.001). Conclusion The incidence has been low prevalence, schools and nurseries are still the focus of control.