Sand production is, a challenging issue in petroleum industry, mainly associated with weak unconsoli-dated formations. A novel testing procedure and a new apparatus were developed to conduct an inte-grated experiment of diagenesis, perforation and sand production on a single large cylindrical artificial sandstone specimen, where solid and fluid pressures can be independently controlled such that realistic reservoir historical conditions can be well simulated in the laboratory. Fluid injection can be performed in both radial and vertical directions, where both single-and two-phase flows can be implemented for study of sand production behaviors at different reservoir's maturity stages. The equipment consists of an intensive instrumentation system to monitor pressures, displacements and material states continuously. The produced sand particles were filtered and monitored in real-time for the study of time-dependent phenomena. The experimental results showed similar patterns to that observed in the field and pro-vided valuable insight for the development of prediction methods for sand production of similar materials.