妊娠合并单纯疱疹病毒(HSV)感染是一个极为严重的围生期问题。新生儿HSV感染几乎都来自母亲临产时产道HSV感染,病毒经破裂之羊膜上行或产时经生殖道感染产儿。不论HSV_1或HSV_2感染,新生儿都可引起脑炎致永久性神经系统损害如小头畸形、轻瘫、僵直性痉挛、癫痫、聋、盲、眼炎、皮损以至全身广泛性损害,死亡率可高达60～74%。此外,近50%胎儿在妊娠30～ Pregnancy complicated with herpes simplex virus (HSV) infection is a very serious perinatal problem. HSV infection in newborns are almost always from the birth of mothers during labor HSV infection, the virus by the rupture of the amniotic membrane up or during delivery of genital tract infections in children. Neonates can cause encephalitis-induced permanent damage to the nervous system such as microcephaly, paresis, stiff spasms, epilepsy, deafness, blindness, ophthalmia, skin lesions, and extensive generalized impairment, regardless of HSV_1 or HSV_2 infection. Up to 60 ~ 74%. In addition, nearly 50% of fetuses in pregnancy 30 ~