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目的：探讨对表现出眶尖综合症的复发颅底肿瘤患者，进行最后的手术挽救效果，客观地审视颅底手术的适应症。方法：回顾性分析了共１０例出现眶尖综合症的颅底肿瘤复发患者，其中１例脑膜瘤和９例来源于鼻腔及副鼻窦的恶性肿瘤，均进行了手术挽救治疗，外科入路分为颅外眶内容剜出（９例）和颅面联合手术（１例）。结果：全组无手术死亡，３例出现术后并发症。所有患者术后疼痛症状有不同程度缓解，但是，只有良性的脑膜瘤患者手术切除彻底，因而无瘤生存３年。其余９例恶性肿瘤未能达到完全切除，其中４例失访（死于肿瘤可能性大），３例死于肿瘤复发，２例带瘤生存。结论：除良性肿瘤外，当颅底复发肿瘤表现出眶尖综合症时，外科手术通常只能达到减症目的。
OBJECTIVE: To investigate the final surgical salvage effect of patients with recurrent skull base tumors that show a hernia syndrome and objectively examine the indications for skull base surgery. Methods: A retrospective analysis of 10 cases of recurrent skull base tumors with orbital syndrome was performed. One case of meningioma and 9 cases of malignant tumors originating from the nasal cavity and paranasal sinus were treated with surgical salvage therapy. For extracranial fistula contents (9 cases) and craniofacial surgery (1 case). Results: There were no operative deaths in the whole group and 3 cases had postoperative complications. All patients had postoperative pain relief in varying degrees. However, only benign meningioma patients were completely resected and had no tumor survival for 3 years. The remaining 9 cases of malignant tumors failed to achieve complete resection. Among them, 4 cases were lost to follow-up (possibly due to tumors), 3 cases died of tumor recurrence, and 2 cases had tumor survival. Conclusion: In addition to benign tumors, when the recurrent tumor in the base of the skull shows a hernia syndrome, surgery usually only achieves the purpose of a reduction.