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目的观察剖宫产术后将喷他佐辛应用于静脉自控镇痛对母乳喂养新生儿神经和适应能力的影响。方法随机选择剖宫产术后采取喷他佐辛静脉自控镇痛技术的产妇60例作为试验组,另选取正常分娩产妇60例为对照组。试验组采用连续硬膜外麻醉,术毕拔除硬膜外导管,采用喷他佐辛进行静脉自控镇痛;对照组不用任何镇痛药物。比较2组产后产妇泌乳及母乳喂养情况及新生儿的体质量、Apgar评分、神经和适应能力评分(NACS)。结果2组新生儿体质量、Apgar评分比较差异均无统计学意义(P>0.05)。产后泌乳及母乳喂养情况组间比较差异无统计学意义(P>0.05)。2组新生儿NACS评分在各时间点的NACS均>35分,组间比较差异无统计学意义(P>0.05)。结论剖宫产术后应用喷他佐辛静脉自控镇痛自控镇痛对新生儿精神、行为无明显不良影响,可安全应用于临床。
Objective To observe the effect of pentazocine applied intravenously on analgesia after cesarean on the nerve and adaptive capacity of breast-fed neonates. Methods Sixty cases of postpartum spontaneous labor analgesia with pentazocine after cesarean section were randomly chosen as the experimental group. Another 60 cases of normal delivery women were selected as the control group. The experimental group was treated with continuous epidural anesthesia, epidural catheter was removed after operation, intravenous controlled analgesia was given with pentazocine, and the control group did not need any analgesic drugs. The postpartum maternal lactation and breastfeeding status, neonatal weight, Apgar score, Nerve and Fitness Score (NACS) were compared between the two groups. Results There was no significant difference in neonatal weight and Apgar score between the two groups (P> 0.05). There was no significant difference between postpartum lactation and breastfeeding (P> 0.05). The NACS scores of neonates in both groups were> 35 points at any time point, and there was no significant difference between the two groups (P> 0.05). Conclusion Application of self-controlled analgesic with pentazocine intravenous analgesia after cesarean section has no adverse effect on the spirit and behavior of neonates and can be safely used in clinical practice.