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目的探讨非典型性胃食管返流病以呼吸道症状为临床表现的诊治情况。方法选取68例非典型性胃食管返流病患者为研究对象,使用胃镜检查和对食管进行24 h pH监测、质子泵抑制剂试用治疗进行确诊,均给予患者质子泵抑制剂和促动力药物进行治疗,观察临床疗效。结果连续治疗4周后,68例患者中,痊愈38例,有效20例,无效10例,总有效率为85.29%。治疗6周后,痊愈55例,有效10例,无效3例,总有效率为95.59%。持续巩固治疗2周后,68例患者全部痊愈,总有效率为100.00%。随访1个月无复发者。结论非典型性胃食管返流病临床易误诊或漏诊,应提高对非典型性胃食管返流病诊治的重视,临床使用质子泵抑制剂试用治疗及促动力药物治疗能够有效治愈胃食管返流疾病,值得推广应用。。
Objective To investigate the diagnosis and treatment of atypical gastroesophageal reflux disease with respiratory symptoms as the clinical manifestation. Methods Sixty-eight patients with atypical gastroesophageal reflux disease were enrolled in this study. Gastroscopy and pH monitoring of the esophagus were performed for 24 h. Proton pump inhibitors were used for diagnosis. Proton pump inhibitors and motility agents were given to patients Treatment, observation of clinical efficacy. Results After 4 weeks of continuous treatment, among the 68 patients, 38 were cured, 20 were effective and 10 were ineffective. The total effective rate was 85.29%. Six weeks after treatment, 55 cases were cured, 10 cases were effective and 3 cases were ineffective. The total effective rate was 95.59%. After two weeks of continuous consolidation therapy, 68 patients were completely cured, with a total effective rate of 100.00%. Follow-up 1 month without recurrence. Conclusion The clinical diagnosis of atypical gastroesophageal reflux disease is easy to misdiagnosis or missed diagnosis. Attention should be paid to the diagnosis and treatment of atypical gastroesophageal reflux disease. The clinical use of proton pump inhibitor trial and pharmacokinetic therapy can effectively cure gastroesophageal reflux Disease, it is worth promoting application. .