2014年5月,《自然》杂志发表了由中国医学科学院肿瘤医院分子肿瘤学国家重点实验室主任詹启敏院士团队与华大基因、汕头大学医学院等合作取得的一项科学成果。食管癌是最为常见的恶性肿瘤之一,也是全世界癌症死亡率第六的肿瘤。全球约70%的食管癌发生在中国,90%以上食管癌的病理为食管鳞状细胞癌(ESCC)。目前,尚缺乏食管鳞状细胞癌的早期诊断和治疗的临床方法,导致患者5年生存率仅为10%。然而,这些全套基因组事件导致 In May 2014, Nature published a scientific achievement made by the team led by Prof. Zhan Qimin, director of the State Key Laboratory of Molecular Oncology, Cancer Institute of Chinese Academy of Medical Sciences and Huada Gene and Shantou University Medical College. Esophageal cancer is one of the most common malignancies and the sixth cancer in the world. About 70% of esophageal cancers worldwide occur in China, and over 90% of esophageal carcinomas are esophageal squamous cell carcinomas (ESCC). At present, there is a lack of clinical methods for the early diagnosis and treatment of esophageal squamous cell carcinoma, resulting in a 5-year survival rate of only 10%. However, these full genome events are causing