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目的分析浙江省德清县2006-2012年甲状腺癌发病状况及趋势,为制定甲状腺癌防治策略提供参考依据。方法病例资料来源于德清县肿瘤发病电子数据库,人口资料来源于统计局,计算甲状腺癌发病率、年龄别发病率、变化百分比(PC%)及年度变化百分比(APC%),来描述发病变化趋势。结果德清县甲状腺癌粗发病率由2006年的4.01/10万升高至2012年的37.72/10万,PC%达684.33%,APC%为46.54%(95%CI为44.12%~49.01%);男性PC%为1 120.69%,APC%为36.41%;女性PC%为603.39%,APC%为46.35%。男性发病率远低于女性,发病比值为0.32。发病年龄高峰组为50~54岁,发病率为30.84%。结论德清县甲状腺癌发病率呈明显上升趋势,男性及女性发病率的年度变化差异均有统计学意义,且变化趋势女性比男性更明显。
Objective To analyze the status and trends of thyroid cancer incidence in Deqing County, Zhejiang Province from 2006 to 2012, and provide a reference for the development of thyroid cancer prevention and treatment strategies. Methods The data of the cases were from the electronic database of cancer incidence in Deqing County. The population data were collected from the Bureau of Statistics. The incidence of thyroid cancer, age-related morbidity, percentage change (PC%) and annual change percentage (APC%) were calculated to describe the change trend . Results The crude incidence of thyroid cancer in Deqing County increased from 4.01 / 100 in 2006 to 37.72 / 100 in 2012, with PC% reaching 684.33% and APC% reaching 46.54% (95% CI: 44.12% ~ 49.01%); PC was 120.69% for men, 36.41% for APC, 603.39% for women, and 46.35% for APC. The incidence of males was much lower than that of females, with a morbidity ratio of 0.32. The peak incidence age group was 50 ~ 54 years old, the incidence rate was 30.84%. Conclusions The incidence of thyroid cancer in Deqing County shows a significant upward trend. The annual changes of the incidence of thyroid cancer in both men and women are statistically significant, and the changing trend is more obvious in women than in men.