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目的探讨无冠心病史的老年患者冠脉钙化情况及影响因素。方法收集本院无冠心病史的92例老年患者的临床资料,采用双源多层螺旋CT(Dual-source spiral computed tomography,DSCT)进行冠状动脉造影,计算钙化积分(Calcification score,CS)。结果无冠脉钙化(CS 0分)3例(3.26%),0分400分为40例(43.48%);与CS≤400组相比,CS>400组年龄偏高(80.50±6.59岁VS 83.40±4.08岁),男性更多(69.23%VS 90.00%),糖尿病比例更高(19.23%VS 45.00%),空腹血糖(5.34±0.92 mmol/L比5.78±1.19 mmol/L)、血清同型半胱氨酸(Homocysteine,Hcy)浓度(13.16±5.23μmol/L VS 17.00±6.68μmol/L)更高(P均<0.05)。结论无冠心病史老年患者冠脉钙化发生率高,冠脉钙化的影响因素有年龄、男性、糖尿病、空腹血糖以及Hcy升高。
Objective To investigate coronary artery calcification in elderly patients without coronary heart disease and its influencing factors. Methods The clinical data of 92 elderly patients without coronary heart disease in our hospital were collected. Coronary angiography was performed by Dual-source spiral computed tomography (DSCT) to calculate Calcification score (CS). Results There were 3 cases (3.26%) without coronary artery calcification (CS 0), 37 cases (40.22%) with CS≤100 points, 12 cases (13.04%) with CS 400 ~ 400 points and 40 cases with CS> 400 (43.48%). CS> 400 group was higher than that of CS≤400 group (80.50 ± 6.59 vs. 83.40 ± 4.08 years old), with more males (69.23% vs 90.00%) and higher proportion of diabetes (19.23% VS 45.00%), fasting blood glucose (5.34 ± 0.92 mmol / L vs 5.78 ± 1.19 mmol / L), and serum Homocysteine concentration (13.16 ± 5.23μmol / L VS 17.00 ± 6.68μmol / L) Higher (all P <0.05). Conclusion The incidence of coronary artery calcification in elderly patients without coronary heart disease is high. The influencing factors of coronary artery calcification are age, male, diabetes, fasting blood glucose and Hcy.