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目的建立动物源性食品中硝基呋喃代谢物的检测方法,对2013年陕西省动物源性食品中硝基呋喃的污染现状进行调查分析。方法按照代表性、适时性和随机性原则在全省范围内采集样品737份,样品经2-硝基苯甲醛衍生化,固相萃取柱净化后采用超高效液相色谱-串联质谱法定量分析。结果动物源性食品中硝基呋喃代谢物的总检出率为3.93%(29/737),鸡肉中的硝基呋喃代谢物的检出率最高(8.05%,14/174),4种硝基呋喃代谢物中呋喃它酮代谢物5-吗啉甲基-3-氨基-2-噁唑烷基酮(AMOZ)的检出率最高(2.04%,15/737)。结论陕西省动物源性食品在一定程度上受到了硝基呋喃的污染,应引起监管部门的注意,加强食品监督管理,保障食品安全。
Objective To establish a method for the determination of nitrofuran metabolites in animal-derived foods, and to investigate the status of nitrofurantid pollution in animal-derived foods in Shaanxi Province in 2013. Methods According to the principle of representativeness, timeliness and randomness, 737 samples were collected in the whole province. The samples were derivatized with 2-nitrobenzaldehyde and purified by solid-phase extraction (SPE) column and analyzed by ultra performance liquid chromatography-tandem mass spectrometry . Results The total detection rate of metabolites of nitrofurans in animal-derived foods was 3.93% (29/737), the highest detection rate of metabolites of nitrofurans in chicken (8.05%, 14/174), four kinds of nitrate The highest detection rate (2.04%, 15/737) of furosemide metabolite 5-morpholinomethyl-3-amino-2-oxazolidinyl ketone (AMOZ) was found in the furazan metabolites. Conclusion Animal-derived foods in Shaanxi Province are contaminated with nitrofurans to a certain extent and should be brought to the attention of regulatory authorities to strengthen food supervision and management and ensure food safety.