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IgA肾病是以反复发作性肉眼或镜下血尿,肾小球系膜细胞增生、基质增多,伴广泛IgA沉积为特点的原发性肾小球疾病,亦称为IgA-IgG系膜沉积性肾炎和1gA系膜性肾炎。本病以血尿为主要症状,或伴有蛋白尿,甚至大量蛋白尿,呈肾病综合征表现,少数患者可出现急进性肾炎综合征。本病属于中医学的“虚劳”“尿血”“腰痛”“肾风”“水肿”等范畴。中医学认为,肾气阴两虚是IgA肾病的基础证候或中心证候;风热上扰及下焦湿热是IgA肾病的初始或短期出现的急性伴发证候;脉络瘀阻及风湿内扰则是IgA肾病气阴两虚证候最常见、最重要的合并证候。本文根据中医学辨证论治、对症用药的理论,从用药原则、用药方案、用药提示等方面,就IgA肾病中成药的合理应用进行了阐述。
IgA nephropathy is a primary glomerular disease characterized by recurrent episodes of gross or microscopic hematuria, mesangial cell proliferation, stromal proliferation, and extensive IgA deposition, also known as IgA-IgG-subphrenic nephritis And 1gA mesangial nephritis. The disease with hematuria as the main symptom, or associated with proteinuria, or even a large amount of proteinuria, showed nephrotic syndrome, a small number of patients with acute nephritic syndrome may occur. The disease belongs to traditional Chinese medicine “consumptive ” “hematuria ” “back pain ” “kidney wind ” “edema ” and other fields. Chinese medicine believes that deficiency of both qi and kidney of the kidney is the basic syndrome or center syndrome of IgA nephropathy; upper and lower wind-heat disturbance and lower anxiety and dampness are the initial or short-term acute syndrome of IgA nephropathy; It is the most common IgA nephropathy Qi and Yin syndrome, the most important syndromes. Based on the theories of syndrome differentiation and treatment of TCM and symptomatic treatment, this article elaborates the rational application of proprietary Chinese medicines in IgA nephropathy from the aspects of medication principles, medication regimens and drug reminders.