阿仑膦酸钠(alendronate sodium)是目前国内最常用的双膦酸盐类药物之一,它不仅能有效抑制破骨细胞的功能,减少骨吸收,而且能促进钙在骨骼中的沉积,提高骨密度,从而降低椎体、髋部和其他部位的骨折风险~([1,2])。最近,在临床工作中,我们发现1例服用华法林抗凝治疗的老年男性骨质疏松症患者,在服用阿仑膦酸钠后,其 Alendronate sodium (alendronate sodium) is currently one of the most commonly used bisphosphonates, which not only can effectively inhibit the function of osteoclasts, reduce bone resorption, but also to promote the deposition of calcium in the bones and improve Bone density, thereby reducing the risk of vertebral body fractures, hip and other parts of ~ ([1,2]). Recently, in clinical work, we found that 1 case of osteoporosis in elderly men taking warfarin anticoagulation therapy, after taking alendronate sodium, its