近年来,由于肾脏活体组织检查的广泛开展,免疫荧光技术及免疫化学技术的发展,以及电子显微镜的广泛应用,对肾小球肾炎发病机理的认识已有很大进展。免疫机制参预肾小球损害这一观点已被广泛接受。Chester概括了免疫机制参预肾小球肾炎的证据,包括1.形态学与免疫病理学方面的改变与某些肾小球肾炎的实验模型相似; In recent years, due to the wide range of renal biopsy, the development of immunofluorescence and immunochemistry, and the widespread use of electron microscopy, great progress has been made in understanding the pathogenesis of glomerulonephritis. The idea that immune mechanisms participate in glomerular damage has been widely accepted. Chester outlines the evidence that immune mechanisms participate in glomerulonephritis, including 1. Morphological and immunopathological changes that are similar to some of the experimental models of glomerulonephritis;