灭菌柜是医院灭菌制剂室必备的大型设备之一。我院使用的灭菌柜系哈尔滨红卫医疗器械厂生产中型(装量500瓶)灭菌柜。在长期使用过程中,我们认为它具有进气快,排气快等优点。但同时我们也发现其不足,即葡萄糖注射液灭菌后5—HMF含量较高(经常超标)、即或不超标,也多偏高(在0.2～0.32间)。我们征得厂家技术人员的认可,对灭菌柜进行局部改造。经两年多的使用,效果较为满意。 The sterilizer is one of the necessary large-scale equipments in the hospital sterilization preparation room. The sterilizer used in our hospital is a medium-sized (500 bottles) sterilization cabinet produced by Harbin Hongwei Medical Instrument Factory. In the long-term use, we think it has the advantages of fast intake, fast exhaust, etc. But at the same time, we also found that its shortcomings, that is, 5-HMF content in the glucose injection after sterilization is high (often exceeding the standard), that is, or not exceeding the standard, but also more high (between 0.2 to 0.32). We obtained the approval of the manufacturer’s technicians and made partial modifications to the sterilizer. After more than two years of use, the effect is more satisfactory.